Department of Disease Control, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
Holster International Research and Development Consultancy, Addis Ababa, Ethiopia.
BMC Med. 2024 Sep 2;22(1):348. doi: 10.1186/s12916-024-03558-x.
School-based water, sanitation and hygiene (WASH) may improve the health and attendance of schoolchildren, particularly post-menarcheal girls, but existing evidence is mixed. We examined the impact of an urban school-based WASH programme (Project WISE) on child health and attendance.
The WISE cluster-randomised trial, conducted in 60 public primary schools in Addis Ababa, Ethiopia over one academic year, enrolled 2-4 randomly selected classes per school (~ 100 pupils) from grades 2 to 8 (aged 7-16) in an 'open cohort'. Schools were assigned 1:1 by stratified randomisation to receive the intervention during the 2021/2022 or the 2022/2023 academic year (waitlist control). The intervention included improvements to drinking water storage, filtration and access, handwashing stations and behaviour change promotion. Planned sanitation improvements were not realised. At four unannounced classroom visits post-intervention (March-June 2022), enumerators recorded primary outcomes of roll-call absence, and pupil-reported respiratory illness and diarrhoea in the past 7 days among pupils present. Analysis was by intention-to-treat.
Of 83 eligible schools, 60 were randomly selected and assigned. In total, 6229 eligible pupils were enrolled (median per school 101.5; IQR 94-112), 5987 enrolled at study initiation (23rd November-22nd December 2021) and the remaining 242 during follow-up. Data were available on roll-call absence for 6166 pupils (99.0%), and pupil-reported illness for 6145 pupils (98.6%). We observed a 16% relative reduction in odds of pupil-reported respiratory illness in the past 7 days during follow-up in intervention vs. control schools (aOR 0.84; 95% CI 0.71-1.00; p = 0.046). There was no evidence of effect on pupil-reported diarrhoea in the past 7 days (aOR 1.15; 95% CI 0.84-1.59; p = 0.39) nor roll-call absence (aOR 1.07; 95% 0.83-1.38; p = 0.59). There was a small increase in menstrual care self-efficacy (aMD 3.32 on 0-100 scale; 95% CI 0.05-6.59), and no evidence of effects on other secondary outcomes.
This large-scale intervention to improve school WASH conditions city-wide had a borderline impact on pupil-reported respiratory illness but no effect on diarrhoeal disease nor pupil absence. Future research should establish relationships between WASH-related illness, absence and other educational outcomes.
ClinicalTrials.gov, number NCT05024890.
基于学校的水、环境卫生和个人卫生(WASH)措施可能会改善学童,尤其是初潮后的女孩的健康和出勤率,但现有证据参差不齐。我们研究了城市基于学校的 WASH 项目(WISE 项目)对儿童健康和出勤率的影响。
WISE 是一项在埃塞俄比亚亚的斯亚贝巴的 60 所公立小学进行的整群随机试验,在一个学年中,每个学校从 2 年级到 8 年级(年龄 7-16 岁)中随机选择 2-4 个班级(约 100 名学生)进入“开放队列”。学校按照分层随机分配 1:1 的比例,在 2021/2022 或 2022/2023 学年接受干预(候补对照)。干预措施包括改善饮用水储存、过滤和获取、洗手站以及促进行为改变。计划中的改善环境卫生条件并未实现。在干预后的四个非通知课堂访问(2022 年 3 月至 6 月)中,计数员记录了在班学生的点名缺勤情况,以及在校学生报告的过去 7 天内的呼吸道疾病和腹泻情况。分析采用意向治疗。
在 83 所符合条件的学校中,有 60 所被随机选中并进行了分配。共有 6229 名符合条件的学生被录取(每所学校的中位数为 101.5;IQR 为 94-112),其中 5987 名学生在研究启动时(2021 年 11 月 23 日至 12 月 22 日)入学,其余 242 名学生在随访期间入学。共有 6166 名学生(99.0%)有完整的点名缺勤数据,6145 名学生(98.6%)有完整的学生报告疾病数据。我们观察到,在干预组与对照组中,过去 7 天内学生报告的呼吸道疾病的比值比(OR)相对减少了 16%(aOR 0.84;95%CI 0.71-1.00;p=0.046)。但干预组与对照组之间,学生报告的过去 7 天内腹泻病(aOR 1.15;95%CI 0.84-1.59;p=0.39)或点名缺勤(aOR 1.07;95%CI 0.83-1.38;p=0.59)均无显著差异。月经护理自我效能感略有增加(0-100 分制中增加 3.32 分;95%CI 0.05-6.59),但其他次要结局均无影响。
这项全市范围内改善学校 WASH 条件的大规模干预措施对学生报告的呼吸道疾病有一定影响,但对腹泻病或学生缺勤率没有影响。未来的研究应建立 WASH 相关疾病、缺勤和其他教育结果之间的关系。
ClinicalTrials.gov,编号 NCT05024890。