Trinies Victoria, Garn Joshua V, Chang Howard H, Freeman Matthew C
Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia
Am J Trop Med Hyg. 2016 Jun 1;94(6):1418-25. doi: 10.4269/ajtmh.15-0757. Epub 2016 Apr 25.
We conducted a matched-control trial in Mali to assess the effectiveness of a comprehensive school-based water, sanitation, and hygiene (WASH) intervention on pupil absence, diarrhea, and respiratory infections. After completion of the intervention, data were collected from 100 beneficiary schools and 100 matched comparison schools in 5-6 sessions over a 14-month period. Data collection included roll calls to assess absenteeism and interviews with a subset of pupils to assess recent absence and disease symptoms. The odds of pupils being absent at roll call were 23% higher in beneficiary schools than in comparison schools (odds ratio [OR]: 1.23, 95% confidence interval [CI]: 1.06, 1.42). The odds of pupils reporting being absent due to diarrhea (OR: 0.73, 95% CI: 0.56, 0.94) or having had diarrhea (OR: 0.71, 95% CI: 0.60, 0.85) or respiratory infection symptoms (OR: 0.75, 95% CI: 0.65, 0.86) in the past week were lower in beneficiary schools compared with comparison schools. We found that a school-based WASH intervention can have a positive effect on reducing rates of illness, as well as absence due to diarrhea. However, we did not find evidence that these health impacts led to a reduction in overall absence. Higher absence rates are less likely attributable to the intervention than the result of an imbalance in unobserved confounders between study groups.
我们在马里进行了一项配对对照试验,以评估基于学校的全面水、环境卫生和个人卫生(WASH)干预措施对学生缺勤、腹泻和呼吸道感染的有效性。干预措施完成后,在14个月的时间里分5至6个阶段从100所受益学校和100所配对的对照学校收集了数据。数据收集包括点名以评估缺勤情况,并对一部分学生进行访谈以评估近期缺勤和疾病症状。受益学校点名时学生缺勤的几率比对照学校高23%(优势比[OR]:1.23,95%置信区间[CI]:1.06,1.42)。与对照学校相比,受益学校的学生报告因腹泻缺勤(OR:0.73,95%CI:0.56,0.94)、曾患腹泻(OR:0.71,95%CI:0.60,0.85)或在过去一周有呼吸道感染症状(OR:0.75,95%CI:0.65,0.86)的几率较低。我们发现,基于学校的WASH干预措施在降低疾病发生率以及因腹泻导致的缺勤方面可以产生积极影响。然而,我们没有发现证据表明这些健康影响会导致总体缺勤率降低。较高的缺勤率不太可能归因于干预措施,而更可能是研究组之间未观察到的混杂因素不平衡的结果。