Salık Yasemin, Eroglu Pelin, Zengin Gökhan, Binzet Rıza
Department of Chemistry, Faculty of Science, Mersin University, Mersin, Türkiye.
Physiology and Biochemistry Research Laboratory, Department of Biology, Faculty of Science, Selcuk University, Konya, Türkiye.
Int J Environ Health Res. 2025 Jun;35(6):1444-1455. doi: 10.1080/09603123.2024.2393433. Epub 2024 Sep 1.
This study aimed to evaluate the phenolic profile, antioxidant, antibacterial, and antidiabetic properties of ethanolic and methanolic extracts of the different parts of the endemic . The antioxidant activities of were determined with 1,1-diphenyl-1-picrylhydrazyl (DPPH) and the copper-reducing antioxidant capacity (CUPRAC) assays. The strongest antioxidant activity was recorded in methanolic root extract (IC:1.68±0.25 μg/mL) for DPPH and ethanolic root (λ0.68±0.20) extract for CUPRAC. Antibacterial activities of the extracts were displayed by the Resazurin Microplate Method (REMA). All plant extracts analyzed demonstrated stronger effects on (ATCC 02026) than those of the standard compound. The in vitro α-amylase and α-glucosidase inhibitory of the plant extract were assessed using the Iodine method. Except for the methanol leaf extract, all other extracts showed strong α-glucosidase inhibitory activity (0.88-2.13 mmolTE/g). These results show that this endemic is a potential natural antioxidant, antibacterial, and enzyme inhibitor source.
本研究旨在评估该特有植物不同部位乙醇提取物和甲醇提取物的酚类成分、抗氧化、抗菌及抗糖尿病特性。采用1,1 - 二苯基 - 1 - 苦基肼（DPPH）和铜还原抗氧化能力（CUPRAC）测定法测定提取物的抗氧化活性。DPPH法中，甲醇根提取物抗氧化活性最强（IC：1.68±0.25μg/mL）；CUPRAC法中，乙醇根提取物抗氧化活性最强（λ0.68±0.20）。采用刃天青微孔板法（REMA）显示提取物的抗菌活性。所有分析的植物提取物对[具体菌株名称未明确]（ATCC 02026）的作用均强于标准化合物。采用碘量法评估植物提取物的体外α - 淀粉酶和α - 葡萄糖苷酶抑制活性。除甲醇叶提取物外，所有其他提取物均表现出较强的α - 葡萄糖苷酶抑制活性（0.88 - 2.13 mmolTE/g）。这些结果表明，这种特有植物是一种潜在的天然抗氧化剂、抗菌剂和酶抑制剂来源。
