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病例报告:通过增加另一根背根神经节电极挽救一名II型复杂性区域疼痛综合征患者的复发性疼痛

Case Report: Rescue of Relapsed Pain in a Patient with Complex Regional Pain Syndrome Type II by Adding Another Dorsal Root Ganglion Lead.

作者信息

Her Yeng F, Churchill Robert A

机构信息

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA.

Mayo Clinic Alix School of Medicine, Mayo Clinic Hospital, Rochester, MN, 55905, USA.

出版信息

Int Med Case Rep J. 2024 Aug 26;17:765-769. doi: 10.2147/IMCRJ.S477303. eCollection 2024.

DOI:10.2147/IMCRJ.S477303
PMID:39220373
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11363934/
Abstract

We present on a patient with complex regional pain syndrome (CRPS) following ankle surgery. Pain was refractory to both conservative and surgical measures including neurotomies, ankle fusion, hardware removal, and spinal cord stimulation (SCS) trial. A dorsal root ganglion (DRG) stimulation trial with lead placements at L4, L5, and S1 provided significant pain and functional improvement. However, during the implantation, we were able to place only two DRG leads at L4 and L5 and not S1 due to difficulties with advancing the lead to the desired location. Nonetheless, the two DRG leads provided 90% pain relief and 75% functional improvement for 9 months. However, the patient experienced pain symptoms similar to that of pre-implant without a clear trigger after 9 months despite no DRG stimulator hardware malfunction or lead migration. A decision was made to re-try implanting the S1 DRG lead, which was successful and provided significant pain relief.

摘要

我们报告了1例踝关节手术后发生复杂性区域疼痛综合征(CRPS)的患者。疼痛对包括神经切断术、踝关节融合术、取出内固定装置以及脊髓刺激(SCS)试验在内的保守和手术措施均无效。在L4、L5和S1处放置电极的背根神经节(DRG)刺激试验使疼痛和功能得到了显著改善。然而,在植入过程中,由于将电极推进到理想位置存在困难,我们仅在L4和L5处放置了两根DRG电极,未在S1处放置。尽管如此,这两根DRG电极在9个月内使疼痛缓解了90%,功能改善了75%。然而,9个月后,尽管DRG刺激器硬件没有故障且电极也未移位,但患者仍出现了与植入前类似的疼痛症状,且无明显诱因。于是决定再次尝试植入S1 DRG电极,此次植入成功并使疼痛得到了显著缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/11363934/7c481158f69f/IMCRJ-17-765-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/11363934/7c481158f69f/IMCRJ-17-765-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dee/11363934/7c481158f69f/IMCRJ-17-765-g0001.jpg

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Adv Ther. 2022 Oct;39(10):4440-4473. doi: 10.1007/s12325-022-02244-9. Epub 2022 Aug 22.
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Stimulation holiday rescues analgesia after habituation and loss of efficacy from 10-kilohertz dorsal column spinal cord stimulation.刺激假期可挽救10千赫兹背柱脊髓刺激习惯化和疗效丧失后的镇痛作用。
Reg Anesth Pain Med. 2022 Aug 19;47(12):722-7. doi: 10.1136/rapm-2022-103881.
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Mechanisms for the Clinical Utility of Low-Frequency Stimulation in Neuromodulation of the Dorsal Root Ganglion.
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