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盆腔癌肉瘤的多学科综合治疗策略:强调先进的诊断性影像学检查和分期手术干预。

Strategic multidisciplinary management of pelvic carcinosarcoma: Emphasizing advanced diagnostic imaging and staged surgical interventions.

作者信息

Louis Mena, Grabill Nathaniel, Cawthon Mariah, Aycinena Fernando, Green Andrew, Ellis Ezra, Rideout Phillip

机构信息

Northeast Georgia Medical Center, General Surgery Department, Gainesville, GA 30501, USA.

Northeast Georgia Medical Center, Colorectal surgery. Gainesville, GA 30501, USA.

出版信息

Radiol Case Rep. 2024 Aug 6;19(10):4583-4598. doi: 10.1016/j.radcr.2024.07.005. eCollection 2024 Oct.

Abstract

Pelvic carcinosarcoma is an aggressive malignancy with significant diagnostic and management hurdles due to its complex vascularity and potential for extensive local invasion. A 59-year-old female presented with severe abdominal pain and significant weight loss, leading to the discovery of a large, complex pelvic mass through CT scans, MRI, and PET CT, suggesting aggressive malignancy. Initial management included a robotic laparoscopic proximal sigmoid loop colostomy to alleviate obstruction. Significant vascularity led to consultations with Vascular Surgery and subsequent preoperative embolization. Definitive surgery involved a supralevator posterior exenteration for en bloc resection of the vagina, mass, and sigmoid colon, combined with a low anterior resection and an omental J flap in anticipation of potential postoperative radiation therapy. This case underscores the importance of integrated imaging and staged surgical interventions in managing pelvic carcinosarcoma, emphasizing a multidisciplinary approach to optimize outcomes and minimize complications.

摘要

盆腔癌肉瘤是一种侵袭性恶性肿瘤,由于其复杂的血管结构和广泛局部侵袭的可能性,在诊断和治疗方面存在重大障碍。一名59岁女性因严重腹痛和显著体重减轻就诊,通过CT扫描、MRI和PET CT发现盆腔有一个巨大的复杂肿块,提示为侵袭性恶性肿瘤。初始治疗包括机器人腹腔镜近端乙状结肠袢式造口术以缓解梗阻。因其丰富的血管结构,遂咨询血管外科并进行了术前栓塞。确定性手术包括经提肌后盆腔脏器清除术,整块切除阴道、肿块和乙状结肠,同时进行低位前切除术和网膜J形瓣转移术,以应对术后可能的放疗。该病例强调了综合影像学检查和分期手术干预在盆腔癌肉瘤治疗中的重要性,突出了多学科方法对于优化治疗效果和减少并发症的意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62b5/11362795/0187becd2342/gr1.jpg

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