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注意缺陷多动障碍及共病:症状重叠问题

Attention deficit hyperactivity disorder and comorbid disorders: issues of overlapping symptoms.

作者信息

Milberger S, Biederman J, Faraone S V, Murphy J, Tsuang M T

机构信息

Pediatric Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114, USA.

出版信息

Am J Psychiatry. 1995 Dec;152(12):1793-9. doi: 10.1176/ajp.152.12.1793.

Abstract

OBJECTIVE

Since some symptoms are shared by both attention deficit hyperactivity disorder (ADHD) and comorbid psychiatric conditions, it is possible that a diagnosis of ADHD is an artifact of the overlapping symptoms. This article focuses on the assessment of the influence of overlapping symptoms on the diagnosis of ADHD.

METHOD

Three groups of subjects were studied: a group of clinically referred children and adolescents, a group of nonreferred adults who were the parents of these children and adolescents, and a group of clinically referred adults with ADHD. The authors assessed the extent of symptom overlap between ADHD and the disorders that frequently co-occur with ADHD; major depression, bipolar disorder, and generalized anxiety disorder. To determine the degree to which this symptom overlap influences these diagnoses, each individual was rediagnosed on the basis of two different techniques that corrected for the overlapping symptoms, a subtraction method and a proportion method.

RESULTS

The majority of subjects who had both ADHD and a comorbid psychiatric disorder maintained their diagnosis of ADHD when the overlapping symptoms were subtracted. Moreover, when overlapping ADHD symptoms were subtracted, on average, 79% maintained their diagnosis of major depression, 56% maintained their diagnosis of bipolar disorder, and 75% maintained their diagnosis of generalized anxiety disorder.

CONCLUSIONS

These findings show that ADHD is not an artifact of symptoms shared with other psychiatric disorders and that the comorbid conditions themselves are not an artifact of overlapping ADHD symptoms.

摘要

目的

由于注意力缺陷多动障碍(ADHD)和共病的精神疾病存在一些共同症状,ADHD的诊断有可能是症状重叠导致的假象。本文重点评估重叠症状对ADHD诊断的影响。

方法

研究了三组受试者:一组是临床转诊的儿童和青少年,一组是这些儿童和青少年的非转诊家长(成人),还有一组是临床转诊的患有ADHD的成人。作者评估了ADHD与经常与之共病的疾病(重度抑郁症、双相情感障碍和广泛性焦虑症)之间症状重叠的程度。为了确定这种症状重叠对这些诊断的影响程度,基于两种校正重叠症状的不同技术对每个个体进行了重新诊断,即减法法和比例法。

结果

当减去重叠症状时,大多数同时患有ADHD和共病精神障碍的受试者仍维持ADHD的诊断。此外,减去ADHD重叠症状后,平均而言,79%的受试者维持重度抑郁症的诊断,56%的受试者维持双相情感障碍的诊断,75%的受试者维持广泛性焦虑症的诊断。

结论

这些发现表明,ADHD不是与其他精神疾病共有的症状导致的假象,而且共病情况本身也不是ADHD重叠症状导致的假象。

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