Department of Nutrition Sciences, Research Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Eat Weight Disord. 2024 Sep 2;29(1):56. doi: 10.1007/s40519-024-01686-0.
The potential dietary inflammatory index (DII) and the phenomenon of obesity have been linked in recent studies, but it is unclear whether this connection is dependent on metabolic status. Therefore, it was thought that this research would be useful in establishing the relationship between obesity phenotypes and DII.
The 5956 people who took part in the Ravansar non-communicable diseases (RaNCD) cohort research (MHNO) were put into four groups: metabolically unhealthy obesity (MUO), metabolically healthy obesity (MHO), metabolically unhealthy non-obesity (MUNO), and metabolically healthy non-obesity. According to the International Diabetes Federation's criteria, MUO exhibits at least two metabolic disorders and have a body mass index of 30 kg/m2 or higher. DII was extracted from the participant's dietary consumption data.
When possible confounders like age, gender, smoking, drinking alcohol, and exercise were taken into account, more adherence to DII was linked to a higher odds of MHO compared to MHNO (OR: 1.44; CI 95% 1.18, 1.75). Additionally, we discovered that greater adherence to DII was significantly related to higher odds for MUO compared to MHNO (OR: 1.67; CI 95% 1.3, 2.15). However, we found no association between adherence to DII and MUNO.
Our findings indicated that greater adherence to DII was significantly associated with higher odds of MUO. However, it substantially increased the chances of both phenotypes of obesity. Level of evidence Level V-Cross-sectional observational study.
最近的研究表明，潜在的饮食炎症指数（DII）与肥胖现象有关，但尚不清楚这种联系是否依赖于代谢状态。因此，人们认为这项研究有助于确定肥胖表型与 DII 之间的关系。
在 MHNO 参与 Ravansar 非传染性疾病（RaNCD）队列研究的 5956 人中，将其分为 4 组：代谢不健康肥胖（MUO）、代谢健康肥胖（MHO）、代谢不健康非肥胖（MUNO）和代谢健康非肥胖。根据国际糖尿病联合会的标准，MUO 表现出至少两种代谢紊乱，且体重指数（BMI）为 30kg/m2 或更高。DII 从参与者的饮食消费数据中提取。
在考虑了年龄、性别、吸烟、饮酒和运动等可能的混杂因素后，与 MHNO 相比，DII 更符合 MHO 的人患 MHO 的几率更高（OR：1.44；95%CI 1.18，1.75）。此外，我们发现，与 MHNO 相比，DII 更符合 MUO 的人患 MUO 的几率显著更高（OR：1.67；95%CI 1.3，2.15）。然而，我们没有发现 DII 与 MUNO 之间的关联。
我们的研究结果表明，DII 更符合 MUO 的几率显著增加。然而，它大大增加了肥胖的两种表型的几率。证据水平 V-横断面观察性研究。
