在存在干扰物质的情况下，二氧化氯与乙酸或柠檬酸以及一种表面活性剂组合，在悬浮液、载体和四场试验中对脊髓灰质炎病毒、腺病毒和鼠诺如病毒的杀病毒活性。
Virucidal activity of chlorine dioxide in combination with acetic acid or citric acid and a surfactant, in presence of interfering substances, against polio-, adeno- and murine norovirus in suspension-, carrier- and four-field tests.
作者信息
Tarka Patryk, Chruściel Arkadiusz, Hreczuch Wiesław, Kanecki Krzysztof, Nitsch-Osuch Aneta
机构信息
Department of Social Medicine and Public Health, Medical University of Warsaw, Warsaw, Poland.
MEXEO, Kedzierzyn-Kozle, Poland.
出版信息
GMS Hyg Infect Control. 2024 Aug 12;19:Doc37. doi: 10.3205/dgkh000492. eCollection 2024.
INTRODUCTION
The aim of the study was to investigate whether the virucidal effectiveness of chlorine dioxid against adenovirus and murine norovirus can be improved by combining it with carboxylic acids and surfactants.
METHOD
The virucidal efficacy against polio-, adeno- and murine norovirus has been tested in presence of interfering substances in the quantitative suspension test according to EN 14476, the carrier test without mechanical action according to EN 16777, and in the four-field test according to EN 16615.Three chlorine-dioxide-based surface disinfectants were tested: a two-component cleaning disinfectant concentrate for large surfaces, a ready-to-use (RTU) foam, and an RTU gel.
RESULTS
Cleaning and disinfecting preparations based on chlorine dioxide, applied at various concentrations, in combination with acetic acid or citric acid and surfactants, are virucidally active against polio-, adeno-, and norovirus after an exposure time of 5 minutes in presence of interfering substances.
引言
本研究的目的是调查二氧化氯与羧酸和表面活性剂结合使用是否能提高其对腺病毒和鼠诺如病毒的杀病毒效果。
方法
根据EN 14476在定量悬浮试验中、根据EN 16777在无机械作用的载体试验中以及根据EN 16615在四场试验中，在存在干扰物质的情况下测试了对脊髓灰质炎病毒、腺病毒和鼠诺如病毒的杀病毒效力。测试了三种基于二氧化氯的表面消毒剂：一种用于大面积表面的两组分清洁消毒浓缩液、一种即用型（RTU）泡沫和一种RTU凝胶。
结果
基于二氧化氯的清洁和消毒制剂，在存在干扰物质的情况下，在暴露5分钟后，以各种浓度与乙酸或柠檬酸和表面活性剂结合使用，对脊髓灰质炎病毒、腺病毒和诺如病毒具有杀病毒活性。
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