Wang Yitong, Li Tianliang, Lin Lixing, Wang Dong, Feng Lingyan
QianWeichang College, Shanghai University Shanghai 200444 China
Materials Genome Institute, Shanghai Engineering Research Center for Integrated Circuits and Advanced Display Materials, Shanghai Engineering Research Center of Organ Repair, Shanghai University Shanghai 200444 China.
RSC Adv. 2024 Sep 2;14(38):27873-27882. doi: 10.1039/d4ra04614e. eCollection 2024 Aug 29.
Safety concerns arising from bacteria present a significant threat to human health, underscoring the pressing need for the exploration of novel antimicrobial materials. Nanozymes, as a new type of nanoscale material, have attracted widespread attention for antibacterial applications owing to their ability to mimic the catalytic activity of natural enzymes. In this work, we have constructed copper-doped cherry blossom carbon dots (Cu-CDs) with excellent peroxidase-like (POD) activity using a one-pot hydrothermal method. The utilization of cherry blossom as a natural material precursor significantly enhances its biocompatibility. Furthermore, the incorporation of copper ions initiates Fenton-like reaction-triggered POD-like catalytic activity, effectively eradicating bacteria by converting hydrogen peroxide (HO) into hydroxyl radicals (·OH). The antibacterial test results demonstrate that Cu-CDs exhibit a bactericidal efficacy of over 90% against () and (). This study presents a novel environmentally friendly nanozyme material derived from natural sources, exhibiting significant antimicrobial properties and offering innovative insights for the advancement of antimicrobial materials.
细菌引发的安全问题对人类健康构成重大威胁，凸显了探索新型抗菌材料的迫切需求。纳米酶作为一种新型纳米材料，因其能够模拟天然酶的催化活性而在抗菌应用中受到广泛关注。在这项工作中，我们采用一锅水热法构建了具有优异类过氧化物酶（POD）活性的铜掺杂樱花碳点（Cu-CDs）。利用樱花作为天然材料前驱体显著提高了其生物相容性。此外，铜离子的掺入引发了类芬顿反应触发的类POD催化活性，通过将过氧化氢（HO）转化为羟基自由基（·OH）有效地根除细菌。抗菌测试结果表明，Cu-CDs对（）和（）表现出超过90%的杀菌效果。本研究提出了一种源自天然来源的新型环保纳米酶材料，具有显著的抗菌性能，并为抗菌材料的发展提供了创新见解。
