From the Department of Religion, Boston University, Boston, Massachusetts.
South Med J. 2024 Sep;117(9):567-569. doi: 10.14423/SMJ.0000000000001727.
In the context of early-phase clinical trials, research subjects often confuse the differences between clinical research and personal treatment. This phenomenon, known as therapeutic misconception, potentially undermines the validity of informed consent. Several interventions have been proposed to help mitigate therapeutic misconception, although few have considered the role of religious belief. This is a notable omission, given that an association between therapeutic misconception and religious belief has been shown to exist. This perspective calls for more research into the nature of the association between therapeutic misconception and religious belief and suggests a framework that may help clinicians and researchers distinguish between the two, thereby bolstering the informed consent process.
在早期临床试验的背景下，研究对象常常混淆临床研究和个人治疗之间的区别。这种现象被称为治疗性误解，可能会破坏知情同意的有效性。已经提出了几种干预措施来帮助减轻治疗性误解，尽管很少有研究考虑到宗教信仰的作用。鉴于已经表明治疗性误解与宗教信仰之间存在关联，这是一个显著的遗漏。这种观点呼吁对治疗性误解和宗教信仰之间的关联本质进行更多的研究，并提出一个可能有助于临床医生和研究人员区分两者的框架，从而加强知情同意过程。
