镁可增强人胰腺弹性蛋白酶对125I标记弹性蛋白的消化作用。
Magnesium enhances human pancreatic elastase digestion of 125I-labeled elastin.
作者信息
Rabaud M, Lefebvre F, Graves P V, Desgranges C, Bricaud H
出版信息
Experientia. 1985 May 15;41(5):628-31. doi: 10.1007/BF02007692.
PMID:3922781
Abstract
The effect of some divalent cations, especially Mg++, on elastinolysis by porcine or human pancreatic elastase has been determined using 125Iodine-labeled elastin as substrate. Elastin degradation was significantly increased in the presence of 10(-3) M Mg++. If elastin was pre-incubated with 0.5 (w/v) Triton, there was a further increase in elastinolysis to 2.6 times the original rate.
摘要
以125碘标记的弹性蛋白为底物，测定了某些二价阳离子，尤其是Mg++，对猪或人胰腺弹性蛋白酶弹性蛋白水解作用的影响。在10(-3) M Mg++存在下，弹性蛋白降解显著增加。如果弹性蛋白预先与0.5（w/v） Triton孵育，弹性蛋白水解作用会进一步增加至原来速率的2.6倍。
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