Rabilloud T, Vincens P, Hubert M, Pennetier J L, Tarroux P
FEBS Lett. 1985 May 20;184(2):278-84. doi: 10.1016/0014-5793(85)80622-0.
Nuclear proteins of normal and heat-shocked Drosophila cells were analysed by two-dimensional electrophoresis. The computerized processing of the gels allowed us to detect 6 proteins strongly induced by the heat treatment, but which were different from the usually described heat-shock proteins. The possible role of these proteins in genetic regulation is discussed, as is the value of this type of approach for the study of other genetic regulation phenomena.
通过二维电泳分析了正常和热休克果蝇细胞的核蛋白。凝胶的计算机处理使我们能够检测到6种因热处理而强烈诱导产生的蛋白质，但它们与通常描述的热休克蛋白不同。讨论了这些蛋白质在基因调控中的可能作用，以及这种方法在研究其他基因调控现象中的价值。
