Leungsuwan Kanjit, Heier Kory R, Henderson Olivia, Ayoub Karam, Alnabelsi Talal, Slade Emily, Gupta Vedant A
University of Kentucky, USA.
Resusc Plus. 2024 Aug 10;19:100737. doi: 10.1016/j.resplu.2024.100737. eCollection 2024 Sep.
Post cardiac arrest left ventricular ejection fraction (LVEF) is routinely assessed, but the implications of this are unknown. This study aimed to assess the association between post cardiac arrest LVEF and survival to hospital discharge.
In this retrospective cohort study, all in-hospital and out of hospital cardiac arrests at our tertiary care center between January 2012 and September 2015 were included. Baseline demographics, clinical data, characteristics of the arrest, and interventions performed were collected. Earliest post cardiac arrest echocardiograms were reviewed with LVEF documented. The primary outcome was survival to discharge.
A total of 736 patients were included in the analysis (mean age 58 years, 44% female). 15% were out of hospital cardiac arrest (24% shockable rhythm). After adjusting for covariates, patients with LVEF < 30% had 36% lower odds of surviving to hospital discharge than those with LVEF 52% (p = 0.014). Shockable initial rhythm and targeted temperature management were associated with improved survival.
After a cardiac arrest, an initial LVEF < 30% is associated with significantly lower odds of survival to hospital discharge.
心脏骤停后左心室射血分数（LVEF）通常会进行评估，但这样做的意义尚不清楚。本研究旨在评估心脏骤停后LVEF与出院生存率之间的关联。
在这项回顾性队列研究中，纳入了2012年1月至2015年9月期间在我们三级医疗中心发生的所有院内和院外心脏骤停病例。收集了基线人口统计学、临床数据、心脏骤停特征及所采取的干预措施。回顾了最早的心脏骤停后超声心动图，记录了LVEF。主要结局是出院生存率。
共有736例患者纳入分析（平均年龄58岁，44%为女性）。15%为院外心脏骤停（24%为可电击心律）。在对协变量进行校正后，LVEF<30%的患者出院生存几率比LVEF≥52%的患者低36%（p = 0.014）。可电击的初始心律和目标温度管理与生存率提高相关。
心脏骤停后，初始LVEF<30%与出院生存率显著降低相关。
