Joseph Patrice, Sun Rochelle, Guiteau Colette, Jean Juste Marc Antoine, Dorvil Nancy, Vilbrun Stalz, Secours Rode, Severe Karine, Raymond Parnel, Cetoute Fernande, Baptiste Wilnide Jean, Forestal Guyrlaine, Cadet Stanley, Marcelin Adias, Deschamps Marie Marcelle, McNairy Margaret L, Dua Akanksha, Cheung Hoi Ching, Pape Jean William, Koenig Serena P
GHESKIO, Port-au-Prince, Haiti.
Harvard University, Cambridge, MA, USA.
Lancet Reg Health Am. 2024 Aug 12;37:100847. doi: 10.1016/j.lana.2024.100847. eCollection 2024 Sep.
There are limited data on the effectiveness of differentiated service delivery (DSD) for HIV care during sociopolitical turmoil. We assessed outcomes with a DSD model of care that includes patient choice between community-based antiretroviral therapy (ART) centres, home-based ART dispensing, or facility-based care at GHESKIO clinic during a period of severe civil unrest in Port-au-Prince, Haiti.
This retrospective analysis included data on patients with at least one HIV visit at GHESKIO between May 1, 2019, and December 31, 2021. Multivariable logistic regression models were used to assess predictors of attending ≥1 community visit during the study period, and failure to attend timely visits. HIV-1 RNA test results were reported among patients who had been ART for ≥3 months at last visit.
Of the 18,625 patients included in the analysis, 9659 (51.9%) attended at least one community visit. The proportion of community visits ranged from 0.3% (2019) to 44.1% (2021). Predictors of ≥1 community visit included male sex (aOR: 1.13; 95% CI: 1.06, 1.20), secondary education (aOR: 1.07; 95% CI: 1.01, 1.14), income > $USD 1.00/day (aOR: 1.24; 95% CI: 1.14, 1.35), longer duration on ART (aOR: 1.08 per additional year; 95% CI: 1.07, 1.09), and residence in Carrefour/Gressier (p < 0.0001 in comparisons with all other zones). Younger age and shorter time on ART were associated with late visits and loss to follow-up. Among 12,586 patients with an on-time final visit who had been on ART for ≥3 months, 11,131 (88.4%) received a viral load test and 9639 (86.6%) had HIV-1 RNA < 1000 copies/mL.
The socio-political situation in Haiti has presented extraordinary challenges to the health care system, but retention and viral suppression rates remain high with a model of community-based HIV care. Additional interventions are needed to improve outcomes for younger patients, and those with shorter time on ART.
No funding.
关于在社会政治动荡期间差异化服务提供(DSD)对艾滋病护理有效性的数据有限。我们评估了一种DSD护理模式的结果,该模式包括患者在社区抗逆转录病毒治疗(ART)中心、家庭ART配药或太子港严重内乱期间在GHESKIO诊所的机构护理之间进行选择。
这项回顾性分析纳入了2019年5月1日至2021年12月31日期间在GHESKIO至少有一次艾滋病就诊记录的患者数据。使用多变量逻辑回归模型评估在研究期间参加≥1次社区就诊的预测因素以及未按时就诊的预测因素。在最后一次就诊时接受ART治疗≥3个月的患者中报告了HIV-1 RNA检测结果。
纳入分析的18625名患者中,9659名(51.9%)参加了至少一次社区就诊。社区就诊比例从2019年的0.3%到2021年的44.1%不等。≥1次社区就诊的预测因素包括男性(调整后比值比:1.13;95%置信区间:1.06,1.20)、中等教育程度(调整后比值比:1.07;95%置信区间:1.01,1.14)、收入>1.00美元/天(调整后比值比:1.24;95%置信区间:1.14,1.35)、ART治疗时间更长(每增加一年调整后比值比:1.08;95%置信区间:1.07,1.09)以及居住在Carrefour/Gressier(与所有其他区域相比,p<0.0001)。年龄较小和ART治疗时间较短与就诊延迟和失访相关。在12586名按时进行最后一次就诊且接受ART治疗≥3个月的患者中,11131名(88.4%)接受了病毒载量检测,9639名(86.6%)的HIV-1 RNA<1000拷贝/mL。
海地的社会政治局势给医疗系统带来了巨大挑战,但基于社区的艾滋病护理模式下的留存率和病毒抑制率仍然很高。需要采取额外的干预措施来改善年轻患者以及ART治疗时间较短患者的治疗结果。
无资金支持。