Hanapi Nurhusna Adibah, Halim Sanihah Abdul, Razak Asrenee Ab, Sapiai Nur Asma
Department of Radiology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kota Bharu, Kelantan, Malaysia.
Hospital Universiti Sains Malaysia, Universiti Sains Malaysia, Health Campus, Jalan Raja Perempuan Zainab II, 16150 Kota Bharu, Kelantan, Malaysia.
Radiol Case Rep. 2024 Aug 10;19(11):4736-4740. doi: 10.1016/j.radcr.2024.07.087. eCollection 2024 Nov.
According to the most recent edition of the DSM V, neurocognitive disorder (NCD), formerly referred to as dementia, is a debilitating condition that progressively diminishes quality of life. It impacts both physical and cognitive domains, including memory and aberrant behavior. If usual presentation is uncertain, perfusion, functional, and molecular imaging are useful. Gold standard marker for the diagnosis of Alzheimer's disease (AD) is FDG PET imaging. Recent studies have shown promising results, whereby the cerebral blood flow in arterial spin labeling (ASL) of MRI and the hypometabolism FDG PET both show a consistent regional abnormality. Therefore, ASL MRI imaging carries a potential role in assisting diagnosis of neurocognitive disorder.
根据最新版的《精神疾病诊断与统计手册》第五版（DSM V），神经认知障碍（NCD），以前称为痴呆，是一种使人衰弱的病症，会逐渐降低生活质量。它影响身体和认知领域，包括记忆和异常行为。如果常规表现不确定，灌注、功能和分子成像则很有用。诊断阿尔茨海默病（AD）的金标准标志物是氟代脱氧葡萄糖正电子发射断层显像（FDG PET）成像。最近的研究显示出了有前景的结果，即磁共振成像（MRI）的动脉自旋标记（ASL）中的脑血流量和FDG PET的代谢减低均显示出一致的区域异常。因此，ASL MRI成像在辅助诊断神经认知障碍方面具有潜在作用。
