泛素羧基末端水解酶L1（UCH-L1）和胶质纤维酸性蛋白（GFAP）：诊断创伤性脑损伤的有效生物标志物。 - Suppr

UCH-L1 and GFAP: Efficient biomarkers for diagnosing traumatic brain injury.

作者信息

Lakshmipriya Thangavel, Gopinath Subash C B

机构信息

Center for Global Health Research, Saveetha Medical College & Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602105, Tamil Nadu, India.

Faculty of Chemical Engineering & Technology, Universiti Malaysia Perlis (UniMAP), 02600, Arau, Perlis, Malaysia.

出版信息

Brain Spine. 2024 Aug 6;4:102913. doi: 10.1016/j.bas.2024.102913. eCollection 2024.

DOI:10.1016/j.bas.2024.102913

PMID:39229482

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11369362/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee3d/11369362/6ed05bf36fe5/gr1.jpg

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UCH-L1 and GFAP: Efficient biomarkers for diagnosing traumatic brain injury.泛素羧基末端水解酶L1（UCH-L1）和胶质纤维酸性蛋白（GFAP）：诊断创伤性脑损伤的有效生物标志物。

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Blood biomarkers for traumatic brain injury: A narrative review of current evidence.创伤性脑损伤的血液生物标志物：当前证据的叙述性综述

Brain Spine. 2023 Dec 14;4:102735. doi: 10.1016/j.bas.2023.102735. eCollection 2024.

Ultrasensitive Determination of Glial-Fibrillary-Acidic-Protein (GFAP) in Human Serum-Matrix with a Label-Free Impedimetric Immunosensor.基于无标记阻抗免疫传感器的人血清基质中神经胶质纤维酸性蛋白（GFAP）的超灵敏测定。

Biosensors (Basel). 2022 Dec 14;12(12):1165. doi: 10.3390/bios12121165.

Development of an electrochemical impedance spectroscopy based biosensor for detection of ubiquitin C-Terminal hydrolase L1.基于电化学阻抗谱的泛素C末端水解酶L1检测生物传感器的研制。

Biosens Bioelectron. 2022 Jul 15;208:114232. doi: 10.1016/j.bios.2022.114232. Epub 2022 Mar 29.

Detection of Glial Fibrillary Acidic Protein in Patient Plasma Using On-Chip Graphene Field-Effect Biosensors, in Comparison with ELISA and Single-Molecule Array.使用片上石墨烯场效应生物传感器检测患者血浆中的神经胶质纤维酸性蛋白，与 ELISA 和单分子阵列进行比较。

ACS Sens. 2022 Jan 28;7(1):253-262. doi: 10.1021/acssensors.1c02232. Epub 2021 Dec 15.

Serum Concentrations of Ubiquitin C-Terminal Hydrolase-L1 and Glial Fibrillary Acidic Protein after Pediatric Traumatic Brain Injury.儿童创伤性脑损伤后血清泛素羧基末端水解酶-L1 和神经胶质纤维酸性蛋白浓度的变化

Sci Rep. 2016 Jun 20;6:28203. doi: 10.1038/srep28203.

Development of surface plasmon resonance imaging biosensors for detection of ubiquitin carboxyl-terminal hydrolase L1.用于检测泛素羧基末端水解酶L1的表面等离子体共振成像生物传感器的研发

Anal Biochem. 2015 Jan 15;469:4-11. doi: 10.1016/j.ab.2014.09.021. Epub 2014 Oct 13.

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J Neurotrauma. 2011 Jun;28(6):861-70. doi: 10.1089/neu.2010.1564. Epub 2011 Apr 8.

Glial fibrillary acidic protein is highly correlated with brain injury.胶质纤维酸性蛋白与脑损伤高度相关。

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UCH-L1 and GFAP: Efficient biomarkers for diagnosing traumatic brain injury.

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