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美黑乳液中含有的外用类固醇:化妆品消费者的危险。

Topical Steroids Sold as Fade Creams in Beauty Supply Stores: A Danger for Cosmetic Consumers.

出版信息

J Drugs Dermatol. 2024 Sep 1;23(9):709-712. doi: 10.36849/JDD.7608.

DOI:10.36849/JDD.7608
PMID:39231069
Abstract

Topical corticosteroids are used extensively in dermatology. Class 1 high potency topical steroids (HPTS) can result in unwanted side effects such as skin hypopigmentation, atrophy, and acneiform eruptions. HPTS are only legally available by prescription to ensure appropriate use in the United States (US). The authors have noticed a recent increase in patients presenting with steroid acne after buying HPTS products in beauty supply stores. These products are marketed as fade creams to treat hyperpigmentation and uneven skin tone. We assessed skincare products containing HPTS (clobetasol or betamethasone) in 33 beauty supply stores in Miami, FL; Washington, DC; and Baltimore, MD. Out of 33 beauty supply stores, 14 (42.42%) contained HPTS skincare products, and they were all located in Miami. Out of 15 stores visited in Miami, 14 (93.33%) contained skincare products with clobetasol, and 5 (33.33%) contained skincare products with both clobetasol and betamethasone. Of the stores selling HPTS skincare products, the number of different brands available ranged from 1 to 7, with an average of 4.21 different brands per store. Our study reveals that HPTS are readily available in over-the-counter skincare products in many beauty supply stores. HPTS skincare products were only available in one of three cities suggesting there may be a regional supplier distributing these products. It may also indicate that there is less oversight of retail stores in Miami with HPTS products. More studies are needed to quantify the availability of these products in different locations throughout the US. Further Studies can help identify this problem and raise awareness among consumers of the dangers of HPTS skincare products in beauty supply stores. J Drugs Dermatol. 2024;23(9):709-712. doi:10.36849/JDD.7608.

摘要

局部皮质类固醇在皮肤科广泛应用。1 类强效外用皮质类固醇(HPTS)可能会导致皮肤色素减退、萎缩和痤疮样疹等不良副作用。在美国,HPTS 只能凭处方合法获得,以确保其在医疗中的合理使用。作者注意到,最近有越来越多的患者在美容用品店购买 HPTS 产品后出现类固醇痤疮。这些产品作为祛斑霜出售,用于治疗色素沉着过度和肤色不均。我们评估了迈阿密、华盛顿特区和巴尔的摩的 33 家美容用品店中含有 HPTS(氯倍他索或倍他米松)的护肤产品。在 33 家美容用品店中,有 14 家(42.42%)含有 HPTS 护肤产品,且均位于迈阿密。在迈阿密的 15 家商店中,有 14 家(93.33%)含有氯倍他索护肤产品,其中 5 家(33.33%)含有氯倍他索和倍他米松护肤产品。销售 HPTS 护肤产品的商店中,不同品牌的数量从 1 到 7 个不等,平均每个商店有 4.21 个不同品牌。我们的研究表明,许多美容用品店的非处方护肤产品中都有 HPTS。在三个城市中只有一个城市有 HPTS 护肤产品,这表明可能有一个区域供应商在分销这些产品。这也可能表明,迈阿密的零售店对 HPTS 产品的监管较少。需要更多的研究来量化美国不同地区这些产品的供应情况。进一步的研究可以帮助确定这个问题,并提高消费者对美容用品店中 HPTS 护肤产品的危险的认识。皮肤病药物杂志。2024;23(9):709-712。doi:10.36849/JDD.7608.

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