Horii Takayuki, Sasaki Jun, Ishii Hidenobu, Sudou Misa, Takaki Reiko, Tokito Takaaki, Azuma Koichi, Hoshino Tomoaki
Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Japan.
Intern Med. 2025 Apr 1;64(7):1085-1088. doi: 10.2169/internalmedicine.4088-24. Epub 2024 Sep 4.
Angiosarcoma is a rare malignancy that can arise from chronic pyothorax. We herein report a 75-year-old Japanese man with a history of tuberculosis who presented with left-sided chest pain that had persisted for 4 months. Chest computed tomography revealed an encapsulated left-sided pleural effusion with chest wall invasion, and histopathology confirmed angiosarcoma arising from a chronic tuberculous pyothorax. Chemotherapy with paclitaxel (80 mg/m weekly) was ineffective and was discontinued after 3 months. Our findings emphasize that physicians should inform patients with chronic tuberculous pyothorax about malignant complications for which chest pain is the initial symptom, in addition to highlighting the need for careful follow-up.
血管肉瘤是一种可起源于慢性脓胸的罕见恶性肿瘤。我们在此报告一名75岁的日本男性，有肺结核病史，出现左侧胸痛并持续4个月。胸部计算机断层扫描显示左侧有包裹性胸腔积液并侵犯胸壁，组织病理学证实血管肉瘤起源于慢性结核性脓胸。使用紫杉醇（80mg/m²每周）化疗无效，3个月后停药。我们的研究结果强调，医生应告知慢性结核性脓胸患者，除了强调需要密切随访外，还要告知其可能出现以胸痛为首发症状的恶性并发症。
