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泰国公共卫生部数据分析中特发性炎性肌病的发病率和患病率。

Incidence and prevalence of idiopathic inflammatory myopathies in Thailand from the Ministry of Public Health data analysis.

机构信息

Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.

出版信息

Sci Rep. 2024 Sep 4;14(1):20646. doi: 10.1038/s41598-024-71633-7.

Abstract

The epidemiology of idiopathic inflammatory myopathies (IIMs) varies by country. Investigating the epidemiological profile among Thai IIMs could help to inform public health policy, potentially leading to cost-reducing strategies. We aimed to assess the prevalence and incidence of IIM in the Thai population between 2017 and 2020. A descriptive epidemiological study was conducted on patients 18 or older, using data from the Information and Communication Technology Center, Ministry of Public Health, with a primary diagnosis of dermatopolymyositis, as indicated by the ICD-10 codes M33. The prevalence and incidence of IIMs were analyzed with their 95% confidence intervals (CIs) and then categorized by sex and region. In 2017, the IIM cases numbered 9,074 among 65,204,797 Thais, resulting in a prevalence of 13.9 per 100,000 population (95% CI 13.6-14.2). IIMs were slightly more prevalent among women than men (16.8 vs 10.9 per 100,000). Between 2018 and 2020, the incidence of IIMs slightly declined from 5.09 (95% CI 4.92-5.27) in 2017 and 4.92 (95% CI 4.76-5.10) in 2019 to 4.43 (95% CI 4.27-4.60) per 100,000 person-years in 2020. The peak age group was 50-69 years. Between 2018 and 2020, the majority of cases occurred in southern Thailand, with incidence rates of 7.60, 8.34, and 8.74 per 100,000 person-years. IIMs are uncommon among Thais, with a peak incidence in individuals between 60 and 69, especially in southern Thailand. The incidence of IIMs decreased between 2019 and 2020, most likely due to the COVID-19 pandemic, which reduced reports and investigations.

摘要

特发性炎性肌病(IIM)的流行病学在不同国家有所不同。研究泰国 IIM 的流行病学特征有助于为公共卫生政策提供信息,可能会导致降低成本的策略。我们旨在评估 2017 年至 2020 年期间泰国人群中 IIM 的患病率和发病率。对年龄在 18 岁或以上的患者进行了描述性流行病学研究,使用了卫生部信息和通信技术中心的数据,其主要诊断为皮肌炎,ICD-10 代码为 M33。分析了 IIM 的患病率和发病率及其 95%置信区间(CI),并按性别和地区进行了分类。2017 年,在 65204797 名泰国人中,有 9074 例 IIM 病例,患病率为 13.9/10 万(95%CI 13.6-14.2)。女性的 IIM 患病率略高于男性(16.8 比 10.9/10 万)。2018 年至 2020 年期间,IIM 的发病率从 2017 年的 5.09(95%CI 4.92-5.27)和 2019 年的 4.92(95%CI 4.76-5.10)略有下降,2020 年降至 4.43/10 万(95%CI 4.27-4.60)。发病高峰年龄组为 50-69 岁。2018 年至 2020 年期间,大多数病例发生在泰国南部,发病率分别为 7.60、8.34 和 8.74/10 万。IM 患者在泰国人中较为少见,发病高峰在 60-69 岁人群中,尤其是在泰国南部。2019 年至 2020 年期间,IIM 的发病率下降,可能是由于 COVID-19 大流行减少了报告和调查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0a0/11375217/8e3a60b980b5/41598_2024_71633_Fig1_HTML.jpg

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