Department of Ophthalmology, Nanchang First Hospital, Nanchang, Jiangxi Province, China.
Expert Rev Med Devices. 2024 Oct;21(10):971-976. doi: 10.1080/17434440.2024.2355294. Epub 2024 Sep 4.
To investigate the diagnostic value of iTrace visual function analyzer, Pentacam 3D anterior segment analysis system and Lens Opacities Classification System III (LOCS III) in assessing lens opacity in patients with age-related cataract (ARC).
A total of 129 patients with ARC admitted to Anonymized from May 2019 to April 2021 were selected as the research objects. The degree of lens opacity was evaluated by LOCS III classification, iTrace and anterior segment analysis.
The Pentacam nucleus staging (PNS) grade was strongly correlated with nuclear color (NC) ( = 0.537, 0.05) and moderately correlated with nuclear opalescence (NO) ( = 0.473, 0.05). The integrated density (IntDen) in 3-mm nuclear region was strongly correlated with NC ( = 0.548, 0.05) and NO ( = 0.539, 0.05). The dysfunctional lens index (DLI) in 3-mm area was negatively correlated with NC (=-0.252, 0.05), NO (=-0.239, 0.05) and posterior subcapsular cataract (=-0.271, 0.05). PNS was weakly negatively correlated with the DLI in 3-mm area (=-0.219, 0.05), and IntDen in 3-mm core area was weakly negatively correlated with the DLI in 3-mm area (=-0.291, 0.05).
A combination of iTrace, anterior segment analysis and LOCS III may be beneficial in objectively assessing the opacity of different regions of the lens.
探讨 iTrace 视觉功能分析仪、Pentacam 3D 眼前节分析系统和 Lens Opacities Classification System III（LOCS III）在评估年龄相关性白内障（ARC）患者晶状体混浊中的诊断价值。
选取 2019 年 5 月至 2021 年 4 月间于我院就诊的 129 例 ARC 患者作为研究对象，采用 LOCS III 分级、iTrace 和眼前节分析系统评估患者晶状体混浊程度。
Pentacam 核分级（PNS）与核颜色（NC）呈强相关（ = 0.537， 0.05），与核混浊（NO）呈中度相关（ = 0.473， 0.05）；3mm 核区积分密度（IntDen）与 NC 呈强相关（ = 0.548， 0.05），与 NO 呈中度相关（ = 0.539， 0.05）；3mm 区域功能障碍晶状体指数（DLI）与 NC 呈负相关（=-0.252， 0.05），与 NO 呈负相关（=-0.239， 0.05），与后囊下白内障呈负相关（=-0.271， 0.05）；PNS 与 3mm 区域 DLI 呈弱负相关（=-0.219， 0.05），3mm 核心区 IntDen 与 3mm 区域 DLI 呈弱负相关（=-0.291， 0.05）。
iTrace、眼前节分析与 LOCS III 相结合，可能有助于客观评估晶状体不同区域的混浊程度。
