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一项针对2025 - 2035年中国终结结核病策略下复发性结核病的建模研究

A Modeling Study Recurrent Tuberculosis Towards End TB Strategy - China, 2025-2035.

作者信息

Li Tao, Du Xin, Jia Zhongwei, Zhao Yanlin

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.

Chinese Center for Disease Control and Prevention, Beijing, China.

出版信息

China CDC Wkly. 2024 Aug 30;6(35):885-890. doi: 10.46234/ccdcw2024.189.

DOI:10.46234/ccdcw2024.189
PMID:39233997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11369061/
Abstract

WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: The recurrence of tuberculosis (TB) following successful treatment presents a significant challenge.

WHAT IS ADDED BY THIS REPORT?: Achieving the global End TB Strategy milestones and targets with the current strategies in China is challenging. However, interventions following recovery to prevent recurrence, in conjunction with preventive treatment for latent TB infection (LTBI), will aid in meeting these objectives.

WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: Implementing interventions to mitigate recurrence is essential for improving TB control strategies both in China and worldwide. Concurrently, the development of new drugs and vaccines should focus on preventing TB recurrence.

摘要

关于该主题已知的信息有哪些?:成功治疗后结核病(TB)的复发带来了重大挑战。

本报告补充了哪些内容?:在中国,采用当前策略实现全球终结结核病战略的里程碑和目标具有挑战性。然而,康复后采取预防复发的干预措施,结合潜伏性结核感染(LTBI)的预防性治疗,将有助于实现这些目标。

对公共卫生实践有何启示?:实施减轻复发的干预措施对于改善中国乃至全球的结核病控制策略至关重要。同时,新药和疫苗的研发应侧重于预防结核病复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728d/11369061/bb9c46bc81c5/ccdcw-6-35-885-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728d/11369061/97b3ab2aca38/ccdcw-6-35-885-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728d/11369061/bb9c46bc81c5/ccdcw-6-35-885-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728d/11369061/97b3ab2aca38/ccdcw-6-35-885-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/728d/11369061/bb9c46bc81c5/ccdcw-6-35-885-2.jpg

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本文引用的文献

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Quantifying the global number of tuberculosis survivors: a modelling study.全球结核病幸存者数量的量化:一项建模研究。
Lancet Infect Dis. 2021 Jul;21(7):984-992. doi: 10.1016/S1473-3099(20)30919-1. Epub 2021 Feb 25.
2
Optimally capturing latency dynamics in models of tuberculosis transmission.最优捕捉结核病传播模型中的潜伏期动态。
Epidemics. 2017 Dec;21:39-47. doi: 10.1016/j.epidem.2017.06.002. Epub 2017 Jun 16.
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Feasibility of achieving the 2025 WHO global tuberculosis targets in South Africa, China, and India: a combined analysis of 11 mathematical models.
实现 2025 年世卫组织全球结核病目标的可行性:南非、中国和印度 11 个数学模型的综合分析。
Lancet Glob Health. 2016 Nov;4(11):e806-e815. doi: 10.1016/S2214-109X(16)30199-1. Epub 2016 Oct 6.
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Lancet. 2000 Oct 28;356(9240):1470-4. doi: 10.1016/S0140-6736(00)02870-1.