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COVID-19 大流行对眼部疾病的影响：KNHANES 2015-2021。

Impact of COVID-19 pandemic on ocular disease: KNHANES 2015-2021.

机构信息

Department of Ophthalmology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Hallym University Medical Center, 1 Shingil-Ro, Youngdeungpo-Gu, Seoul, 07441, Republic of Korea.

Hallym BioEyeTech Research Center, College of Medicine, Hallym University, Seoul, Republic of Korea.

出版信息

Sci Rep. 2024 Sep 5;14(1):20706. doi: 10.1038/s41598-024-70767-y.

DOI:10.1038/s41598-024-70767-y
PMID:39237530
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11377421/
Abstract

The aim of this study was to evaluate the impact of COVID-19 on ocular diseases and changes in risk factors before and after the COVID-19 pandemic. This study was conducted using data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2015-2021, a national cross-sectional health examination and survey. Associations between ocular diseases and risk factors were determined using the chi-squared test and logistic regression analysis. Bivariable adjusted logistic regression analysis was performed to examine the odds ratio (OR) and 95% confidence interval (CI) to evaluate of the impact of COVID-19 on ocular diseases. Individuals were divided into two age groups (< 60 and ≥ 60 years). A total of 50,158 people were diagnosed, of whom 7270 were diagnosed with cataract, 921 with glaucoma, and 439 with age-related macular degeneration (AMD). Risk factors for cataract were COVID-19 pandemic (OR 1.161), hypertension (OR 1.608), diabetes (OR 1.573), dyslipidemia (OR 1.167), stroke (OR 1.272), and depression (OR 1.567). Risk factors for AMD were COVID-19 pandemic (OR 1.600), dyslipidemia (OR 1.610), and depression (OR 1.466). Risk factors for glaucoma were hypertension (OR 1.234), dyslipidemia (OR 1.529), diabetes (OR 1.323), and depression (OR 1.830). The COVID-19 pandemic was a risk factor for cataracts and AMD, but not for glaucoma. Cataracts and AMD may be more influenced by the acquired health conditions or the environment.

摘要

本研究旨在评估 COVID-19 对眼部疾病的影响，以及 COVID-19 大流行前后危险因素的变化。本研究使用了 2015-2021 年韩国国家健康和营养检查调查（KNHANES）的数据，这是一项全国性的横断面健康检查和调查。使用卡方检验和逻辑回归分析确定眼部疾病与危险因素之间的关联。使用双变量调整的逻辑回归分析来检查 COVID-19 对眼部疾病的影响的比值比（OR）和 95%置信区间（CI）。将个体分为两个年龄组（<60 岁和≥60 岁）。共有 50158 人被诊断出患有白内障，其中 7270 人被诊断出患有青光眼，921 人被诊断出患有年龄相关性黄斑变性（AMD）。白内障的危险因素包括 COVID-19 大流行（OR 1.161）、高血压（OR 1.608）、糖尿病（OR 1.573）、血脂异常（OR 1.167）、中风（OR 1.272）和抑郁（OR 1.567）。AMD 的危险因素包括 COVID-19 大流行（OR 1.600）、血脂异常（OR 1.610）和抑郁（OR 1.466）。青光眼的危险因素包括高血压（OR 1.234）、血脂异常（OR 1.529）、糖尿病（OR 1.323）和抑郁（OR 1.830）。COVID-19 大流行是白内障和 AMD 的危险因素，但不是青光眼的危险因素。白内障和 AMD 可能更多地受到后天健康状况或环境的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0425/11377421/7b1441474812/41598_2024_70767_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0425/11377421/080b760c17bc/41598_2024_70767_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0425/11377421/7b1441474812/41598_2024_70767_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0425/11377421/080b760c17bc/41598_2024_70767_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0425/11377421/7b1441474812/41598_2024_70767_Fig2_HTML.jpg

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