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新冠大流行前后抑郁的流行状况及相关因素:来自韩国国家健康和营养检查调查的结果。

Prevalence and Related Factors of Depression Before and During the COVID-19 Pandemic: Findings From the Korea National Health and Nutrition Examination Survey.

机构信息

Department of Neurology, Seoul National University Hospital, Seoul, Korea.

Instituite of Public Health and Medical Care, Seoul National University Hospital, Seoul, Korea.

出版信息

J Korean Med Sci. 2023 Mar 13;38(10):e74. doi: 10.3346/jkms.2023.38.e74.

Abstract

BACKGROUND

The coronavirus disease 2019 (COVID-19) pandemic has greatly altered the daily lives of people in unprecedented ways, causing a variety of mental health problems. In this study, we aimed to evaluate the prevalence of depression among Korean adults during the COVID-19 pandemic and explore the factors associated with depressive mood using data from the Korea National Health and Nutrition Survey (KNHANES).

METHODS

We analyzed participants aged ≥ 19 years from KNHANES 2018 (n = 5,837) and 2020 (n = 5,265) to measure and compare the prevalence of depression before and during the COVID-19 pandemic. Depression was defined as a score ≥ 10 on the Patient Health Questionnaire-9. Furthermore, we performed a multivariate logistic regression analysis to investigate the independent predictors of depressive mood during the COVID-19 pandemic.

RESULTS

The prevalence of depression was notably higher during the COVID-19 pandemic than in the pre-pandemic period (5.2% vs. 4.3%, = 0.043). In a multivariate model, female sex (adjusted odds ratio [aOR], 1.63; 95% confidence interval [CI], 1.10-2.41), age < 50 years (19-29 years: aOR, 7.31; 95% CI, 2.40-22.21; 30-39 years: aOR, 7.38; 95% CI, 2.66-20.47; 40-49 years: aOR, 4.94; 95% CI, 1.84-13.31 compared to ≥ 80 years), unemployment (aOR, 2.00; 95% CI, 1.41-2.85), upper-middle class household income (aOR, 1.83; 95% CI, 1.18-2.85 compared to upper-class income), being a beneficiary of Medicaid (aOR, 2.35; 95% CI, 1.33-4.14), poor self-rated health (aOR, 4.99; 95% CI, 1.51-3.47 compared to good self-rated health), and current smoking (aOR, 2.29; 95% CI, 1.51-3.47) were found to be significant risk factors for depression during the pandemic.

CONCLUSION

Depression was significantly more prevalent among Korean adults during the COVID-19 pandemic than in the pre-pandemic era. Therefore, more attention should be paid to individuals vulnerable to depression during pandemics. Implementing psychological support public policies and developing interventions to prevent the adverse outcomes of COVID-19-related depression should be considered.

摘要

背景

2019 年冠状病毒病(COVID-19)大流行以史无前例的方式极大地改变了人们的日常生活,导致了各种心理健康问题。在本研究中,我们旨在评估 COVID-19 大流行期间韩国成年人的抑郁患病率,并使用韩国国民健康与营养调查(KNHANES)的数据探讨与抑郁情绪相关的因素。

方法

我们分析了 KNHANES 2018 年(n=5837)和 2020 年(n=5265)≥19 岁的参与者,以测量和比较 COVID-19 大流行前后抑郁的患病率。抑郁定义为患者健康问卷-9 的得分≥10。此外,我们进行了多变量逻辑回归分析,以调查 COVID-19 大流行期间抑郁情绪的独立预测因素。

结果

COVID-19 大流行期间的抑郁患病率明显高于大流行前(5.2% vs. 4.3%,=0.043)。在多变量模型中,女性(调整优势比[aOR],1.63;95%置信区间[CI],1.10-2.41)、年龄<50 岁(19-29 岁:aOR,7.31;95%CI,2.40-22.21;30-39 岁:aOR,7.38;95%CI,2.66-20.47;40-49 岁:aOR,4.94;95%CI,1.84-13.31 与≥80 岁相比)、失业(aOR,2.00;95%CI,1.41-2.85)、中上阶层家庭收入(aOR,1.83;95%CI,1.18-2.85 与高收入阶层相比)、享受医疗补助(aOR,2.35;95%CI,1.33-4.14)、自我评估健康状况差(aOR,4.99;95%CI,1.51-3.47 与自我评估健康状况良好相比)和当前吸烟(aOR,2.29;95%CI,1.51-3.47)被发现是 COVID-19 大流行期间抑郁的显著危险因素。

结论

COVID-19 大流行期间韩国成年人的抑郁患病率明显高于大流行前。因此,应更加关注在大流行期间易患抑郁的个体。应考虑实施心理支持公共政策和制定干预措施,以预防与 COVID-19 相关的抑郁的不良后果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2e0/10010913/499a0c47cf28/jkms-38-e74-g001.jpg

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