Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam.
Falculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam.
J Int Med Res. 2024 Sep;52(9):3000605241277401. doi: 10.1177/03000605241277401.
Eosinophilic gastroenteritis poses a significant diagnostic challenge, particularly in developing countries, where the awareness of this condition may be limited. Here, the case of a patient in her early 30s, who presented with recurrent episodes of abdominal pain and diarrhea, is reported. Initial standard laboratory investigations revealed normal complete blood counts and elevated total serum immunoglobulin E levels. Upper and lower endoscopic evaluations with systemic biopsies did not reveal any significant abnormalities. However, computed tomography revealed a thickened small intestine wall, halo signs, and mild ascites. Analysis of the ascitic fluid confirmed eosinophilia. These findings prompted a diagnosis of eosinophilic gastroenteritis. The patient responded well to a targeted elimination diet, corticosteroids, and antileukotriene medication. The present case emphasizes the importance of considering eosinophilic gastroenteritis in the differential diagnosis of patients who present with abdominal pain and eosinophilic ascites.
嗜酸粒细胞性胃肠炎诊断困难，尤其在发展中国家，对此病的认识可能有限。本文报告了一位 30 多岁的女性患者，反复发作腹痛和腹泻。初步的标准实验室检查显示全血细胞计数正常，总血清免疫球蛋白 E 水平升高。上、下内窥镜检查和全身活检均未发现明显异常。但计算机断层扫描显示小肠壁增厚、晕征和轻度腹水。腹水分析证实存在嗜酸性粒细胞增多。这些发现提示嗜酸粒细胞性胃肠炎的诊断。该患者对靶向消除饮食、皮质类固醇和抗白三烯药物治疗反应良好。本病例强调了在诊断腹痛和嗜酸性腹水患者时，考虑嗜酸粒细胞性胃肠炎的重要性。
