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梅奥粘连概率评分作为机器人辅助部分肾切除术术后肾功能的预测指标

The Mayo Adhesive Probability Score as a Predictor of Postoperative Renal Function in Robot-assisted Partial Nephrectomy.

作者信息

Matsuzaki Hiroshi, Tsubouchi Kazuna, Okabe Y U, Miyazaki Takeshi, Gunge Naotaka, Tominaga Kosuke, Fukuhara Yuichiro, Tachibana Masahiro, Nakagawa Chizuru, Yamazaki Fumihiro, Nakamura Nobuyuki, Haga Nobuhiro

机构信息

Department of Urology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.

出版信息

Cancer Diagn Progn. 2024 Sep 1;4(5):652-657. doi: 10.21873/cdp.10377. eCollection 2024 Sep-Oct.

Abstract

BACKGROUND/AIM: The aim of this study was to evaluate the Mayo Adhesive Probability (MAP) score as a predictor of split renal function deterioration after robot-assisted partial nephrectomy (RAPN).

PATIENTS AND METHODS

A total of 30 patients who underwent RAPN were identified retrospectively. The parameters evaluated included patient characteristics, tumor diameter, MAP score, warm ischemic time (WIT), and renal function. Split renal function was evaluated using Tc-99m DTPA renal scintigraphy before and six months after surgery. Univariate and multivariate logistic regression analyses were performed.

RESULTS

Nine patients (30.0%) showed more than 90% preservation of split renal function on the operated side. The MAP score (p=0.015), cT1b tumor (p=0.0002), and WIT (p=0.044) were associated with preservation of split renal function six months after surgery on univariate analysis. The MAP score was the strongest predictor of preservation of split renal function six months after surgery on multivariable analysis (p=0.007). On receiver-operating characteristic (ROC) curve analysis, the MAP score (cutoff value 3.0; p=0.01) was a significant predictor of split renal function six months after surgery.

CONCLUSION

The MAP score was significantly associated with postoperative split renal function six months after RAPN on the operated kidney side. The MAP score is useful for predicting split renal function after RAPN.

摘要

背景/目的:本研究旨在评估梅奥粘连概率(MAP)评分作为机器人辅助部分肾切除术(RAPN)后分肾功能恶化预测指标的价值。

患者与方法

回顾性纳入30例行RAPN的患者。评估的参数包括患者特征、肿瘤直径、MAP评分、热缺血时间(WIT)和肾功能。术前及术后6个月采用Tc-99m二巯丁二酸(DTPA)肾动态显像评估分肾功能。进行单因素和多因素逻辑回归分析。

结果

9例患者(30.0%)患侧分肾功能保留超过90%。单因素分析显示,MAP评分(p=0.015)、cT1b期肿瘤(p=0.0002)和WIT(p=0.044)与术后6个月分肾功能的保留相关。多因素分析显示,MAP评分是术后6个月分肾功能保留的最强预测指标(p=0.007)。在受试者工作特征(ROC)曲线分析中,MAP评分(临界值3.0;p=0.01)是术后6个月分肾功能的显著预测指标。

结论

MAP评分与RAPN术后6个月患侧分肾功能显著相关。MAP评分有助于预测RAPN后的分肾功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ec5/11372686/aa6c704eac2e/cdp-4-653-g0001.jpg

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