Kaimal Vinitha G, Pai Anuradha
Department of Oral Medicine and Radiology, The Oxford Dental College, Bommanahalli, 560068 Bangalore India.
Indian J Surg Oncol. 2024 Sep;15(3):495-498. doi: 10.1007/s13193-024-01933-x. Epub 2024 Apr 3.
After plasma cell neoplasia, osteosarcoma is the most common primary bone tumor which accounts for 20% of all sarcomas. A malignant tumor is characterized by the formation of bone or osteoid by tumor cells. Long bones are the most common site of involvement. In the jaw bones, approximately 5% of involvement with an incidence of 1 in 1.5 million persons per year. It develops in a broad range of ages but is more common in the third and fourth decades, slightly more often in the mandible than in the maxilla. In this case report, a 24-year-old male patient reported a mass in the left mandible for the past 1 week which appeared after the third molar extraction. In the orthopantomogram, a loss of lamina dura and a change in the trabecular pattern was noted. Histopathological findings were suggestive of osteoblastic osteogenic sarcoma. The patient underwent a hemi-mandibulectomy followed by chemotherapy. The main aim of this case report was to focus on the importance of early diagnosis of this tumor based on clinical and radiographic examinations, particularly taking into account the fast progression and aggressiveness of this neoplasm.
在浆细胞肿瘤之后,骨肉瘤是最常见的原发性骨肿瘤,占所有肉瘤的20%。恶性肿瘤的特征是肿瘤细胞形成骨或骨样组织。长骨是最常受累的部位。在颌骨中,约5%的病例受累,每年发病率为1/150万。它在广泛的年龄范围内发病,但在第三和第四个十年更为常见,在下颌骨比在上颌骨更常见。在本病例报告中,一名24岁男性患者报告在拔除第三磨牙后1周左侧下颌骨出现肿物。在全景片上,可见硬骨板缺失和小梁模式改变。组织病理学检查结果提示为成骨性骨肉瘤。患者接受了半侧下颌骨切除术,随后进行化疗。本病例报告的主要目的是强调基于临床和影像学检查对该肿瘤进行早期诊断的重要性,尤其要考虑到该肿瘤进展迅速且具有侵袭性。