Ciftci Mukaddes Damla, Serin Gurdeniz, Ceylan Naim, Yeniay Levent, Palamar Melis
Department of Ophthalmology, Ege University, Izmir, Türkiye.
Department of Pathology, Ege University, Izmir, Türkiye.
Beyoglu Eye J. 2024 Sep 1;9(3):155-160. doi: 10.14744/bej.2024.83193. eCollection 2024.
Metastatic disease is a relatively rare cause of orbital tumors. While many different types of primary malignancies have been documented, lung and breast cancers are the most prevalent ones among them. Herein, three cases of orbital metastasis from breast cancer are reported. The first patient had no history of primary malignancy, and the initial presentation was orbital metastasis from advanced breast cancer. The second patient had a history of neo-adjuvant chemotherapy, mastectomy, and adjuvant radiotherapy. The recurrence of the disease was diagnosed via symptomatic metastasis to orbit involving the lateral rectus muscle. The third patient had a history of mastectomy, adjuvant radiotherapy, and hormone therapy. Considering that even patients without a diagnosis of primary malignancy may present with orbital metastasis, ophthalmologists' awareness of this issue is critical.
转移性疾病是眼眶肿瘤相对少见的病因。虽然已记录了许多不同类型的原发性恶性肿瘤，但其中最常见的是肺癌和乳腺癌。在此报告三例乳腺癌眼眶转移病例。首例患者无原发性恶性肿瘤病史，最初表现为晚期乳腺癌眼眶转移。第二例患者有新辅助化疗、乳房切除术和辅助放疗史，通过累及外直肌的眼眶症状性转移诊断为疾病复发。第三例患者有乳房切除术、辅助放疗和激素治疗史。鉴于即使未诊断出原发性恶性肿瘤的患者也可能出现眼眶转移，眼科医生对此问题的认识至关重要。
