Department of Ophthalmology, Health Sciences University Antalya Training and Research Hospital, Antalya, Turkey.
Department of Ophthalmology, Health Sciences University Antalya Training and Research Hospital, Varlık mah 100. Yıl cad, 07070, Muratpasa, Antalya, Turkey.
Radiologie (Heidelb). 2024 Nov;64(Suppl 1):153-159. doi: 10.1007/s00117-024-01358-1. Epub 2024 Sep 6.
Central serous chorioretinopathy (CSC) is a systemic disease more than a disease localized to the eye, and there may be vascular involvement in its pathogenesis.
This study aimed to evaluate the carotid intima-media thickness (IMT) of patients with CSC, to compare it with that of healthy individuals, and to explore whether there might be an association between CSC and subclinical carotid atherosclerotic disease.
Adult patients with CSC (n = 30) and healthy individuals (n = 30) were included in this prospective study. All participants underwent complete ophthalmologic imaging and were then referred to the radiology department. Carotid IMT measurements were performed using ultrasound imaging. Measurements of the two groups were obtained and compared.
There was no statistically significant difference between patients with CSC and the control group with respect to age, gender, and smoking habits. The mean (±standard deviation, SD) carotid IMT values obtained by ultrasound measurements for the right and left sides in the patient group were 0.71 mm (± 0.19) and 0.71 mm (± 0.21), respectively. The mean (±SD) carotid IMT values for the right and left sides in the control group were 0.61 mm (± 0.15) and 0.60 mm (± 0.15), respectively. The mean carotid IMT values in the patient group were significantly higher than those in the control group for the right and left sides (p = 0.02 and p = 0.03, respectively).
Carotid IMT is increased in patients with CSC compared to healthy individuals. This outcome might reinforce the benefit of carotid artery screening following diagnosis of CSC by ophthalmologists for early detection of subclinical carotid atherosclerotic disease.
中心性浆液性脉络膜视网膜病变（CSC）是一种全身性疾病，而不仅仅局限于眼部疾病，其发病机制可能涉及血管。
本研究旨在评估 CSC 患者的颈动脉内膜中层厚度（IMT），并与健康个体进行比较，探讨 CSC 是否与亚临床颈动脉粥样硬化疾病有关。
这项前瞻性研究纳入了 30 例 CSC 成年患者和 30 名健康个体。所有参与者均接受了全面的眼科影像学检查，随后转至放射科。使用超声成像测量颈动脉 IMT。对两组的测量值进行了获取和比较。
CSC 患者与对照组在年龄、性别和吸烟习惯方面无统计学差异。超声测量的患者组右侧和左侧颈动脉 IMT 的平均值（±标准差，SD）分别为 0.71 mm（±0.19）和 0.71 mm（±0.21）。对照组右侧和左侧颈动脉 IMT 的平均值（±SD）分别为 0.61 mm（±0.15）和 0.60 mm（±0.15）。患者组右侧和左侧颈动脉 IMT 的平均值明显高于对照组（p=0.02 和 p=0.03）。
与健康个体相比，CSC 患者的颈动脉 IMT 增加。这一结果可能支持眼科医生在诊断 CSC 后对颈动脉进行筛查，以早期发现亚临床颈动脉粥样硬化疾病。
