基于理性设计的红光吸收钌多吡啶配合物作为光动力治疗的光敏剂。
Rational design of a red-light absorbing ruthenium polypyridine complex as a photosensitizer for photodynamic therapy.
机构信息
Faculty of Chemistry and Biochemistry, Ruhr-University Bochum, Universitätsstrasse 150, 44780 Bochum, Germany.
出版信息
Chem Commun (Camb). 2024 Sep 24;60(77):10724-10727. doi: 10.1039/d4cc04126g.
PMID:39240534
Abstract
Herein, the computer-guided design, chemical synthesis, and biological evaluation of a RuC polypyridine complex, that could eradicate cancerous cells upon excitation with red light at 630 nm, is reported.
摘要
本文报道了一种 RuC 多吡啶配合物的计算机辅助设计、化学合成和生物学评价，该配合物在 630nm 红光激发下可以消灭癌细胞。
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