肺出血并发韦格纳肉芽肿和显微镜下多动脉炎。
Pulmonary haemorrhage complicating Wegener's granulomatosis and microscopic polyarteritis.
作者信息
Haworth S J, Savage C O, Carr D, Hughes J M, Rees A J
出版信息
Br Med J (Clin Res Ed). 1985 Jun 15;290(6484):1775-8. doi: 10.1136/bmj.290.6484.1775.
Abstract
The incidence and characteristics of pulmonary haemorrhage in a series of 89 patients with systemic vasculitis were analysed. Pulmonary haemorrhage occurred in 32 of these patients and was associated with haemoptysis in all 32, alveolar shadowing in the chest radiograph in 28, and a significantly raised transfer coefficient in 30. Pulmonary haemorrhage usually resolved with treatment by immunosuppressive drugs but was the cause of death in 11 patients. In contrast with patients with antibasement membrane antibodies there was no correlation between pulmonary haemorrhage and cigarette smoking. Pulmonary haemorrhage is a cause of serious morbidity in patients with systemic vasculitis.
摘要
分析了89例系统性血管炎患者肺出血的发生率及特征。这些患者中有32例发生肺出血，所有32例均伴有咯血，28例胸部X线片有肺泡阴影，30例转运系数显著升高。肺出血通常经免疫抑制药物治疗后缓解，但11例患者死于肺出血。与抗基底膜抗体患者不同，肺出血与吸烟之间无相关性。肺出血是系统性血管炎患者严重发病的原因之一。
相似文献
1
Pulmonary haemorrhage complicating Wegener's granulomatosis and microscopic polyarteritis.肺出血并发韦格纳肉芽肿和显微镜下多动脉炎。
Br Med J (Clin Res Ed). 1985 Jun 15;290(6484):1775-8. doi: 10.1136/bmj.290.6484.1775.
2
Wegener's granulomatosis. Associated with diffuse pulmonary hemorrhage.韦格纳肉芽肿病。与弥漫性肺出血相关。
Acta Pathol Jpn. 1992 Sep;42(9):657-61. doi: 10.1111/j.1440-1827.1992.tb03047.x.
3
Capillaritis and pulmonary hemorrhage in Wegener's granulomatosis.
Am J Surg Pathol. 1989 Jan;13(1):78-9. doi: 10.1097/00000478-198901000-00012.
4
A case of Wegener's granulomatosis complicated by diffuse pulmonary hemorrhage and thrombotic thrombocytopenic purpura.1例韦格纳肉芽肿合并弥漫性肺出血及血栓性血小板减少性紫癜
Korean J Intern Med. 1998 Feb;13(1):68-71. doi: 10.3904/kjim.1998.13.1.68.
5
Wegener's granulomatosis presenting with diffuse alveolar hemorrhage and negative antineutrophilic cytoplasmic antibody test.
Mil Med. 2006 Aug;171(8):781-3. doi: 10.7205/milmed.171.8.781.
6
Wegener's granulomatosis presenting as diffuse pulmonary hemorrhage.表现为弥漫性肺出血的韦格纳肉芽肿病。
Intensive Care Med. 1991;17(2):118-20. doi: 10.1007/BF01691435.
7
Diffuse alveolar haemorrhage in granulomatosis with polyangitis (Wegener's) with coexistent rheumatoid arthritis.显微镜下多血管炎（韦格纳肉芽肿）合并类风湿关节炎时的弥漫性肺泡出血
BMJ Case Rep. 2012 Aug 8;2012:bcr2012006184. doi: 10.1136/bcr.2012.006184.
8
Respiratory system involvement in systemic vasculitides.系统性血管炎中的呼吸系统受累情况。
Clin Exp Rheumatol. 2006 Mar-Apr;24(2 Suppl 41):S48-59.
9
Wegener's granulomatosis and alveolar hemorrhage - case report.韦格纳肉芽肿病与肺泡出血——病例报告
Acta Reumatol Port. 2013 Oct-Dec;38(4):295-8.
10
Limited form of Wegener's granulomatosis.局限性韦格纳肉芽肿
Chest. 1976 Sep;70(03):384-5. doi: 10.1378/chest.70.3.384.
引用本文的文献
1
Limited Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Presenting With Diffuse Alveolar Hemorrhage: A Case Report and Literature Review.以弥漫性肺泡出血为表现的局限性抗中性粒细胞胞浆抗体相关性血管炎：一例报告及文献复习
Cureus. 2024 Jun 20;16(6):e62759. doi: 10.7759/cureus.62759. eCollection 2024 Jun.
2
Alveolar Hemorrhage in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: Results of an International Randomized Controlled Trial (PEXIVAS).抗中性粒细胞胞浆抗体相关性血管炎的肺泡出血：一项国际随机对照试验（PEXIVAS）的结果。
Am J Respir Crit Care Med. 2024 May 1;209(9):1141-1151. doi: 10.1164/rccm.202308-1426OC.
3
Pulmonary renal syndrome: a clinical review.肺肾综合征：临床综述
Breathe (Sheff). 2022 Dec;18(4):220208. doi: 10.1183/20734735.0208-2022. Epub 2023 Jan 10.
4
Granulomatosis With Polyangiitis Complicated by Diffuse Alveolar Hemorrhage, Splenic Infarction and Stroke.肉芽肿性多血管炎合并弥漫性肺泡出血、脾梗死和中风。
Cureus. 2022 Oct 9;14(10):e30102. doi: 10.7759/cureus.30102. eCollection 2022 Oct.
5
A novel therapeutic strategy using extracorporeal membrane oxygenation in patients with anti-neutrophil cytoplasmic antibodies-associated vasculitis: a case report and literature review.一种在抗中性粒细胞胞浆抗体相关性血管炎患者中使用体外膜肺氧合的新型治疗策略：一例报告及文献综述
Ann Transl Med. 2021 Aug;9(15):1267. doi: 10.21037/atm-21-3133.
6
Interstitial Lung Disease and Diffuse Alveolar Hemorrhage, the Two Key Pulmonary Manifestations in Microscopic Polyangiitis.间质性肺病与弥漫性肺泡出血，显微镜下多血管炎的两种关键肺部表现。
Tuberc Respir Dis (Seoul). 2021 Oct;84(4):255-262. doi: 10.4046/trd.2021.0065. Epub 2021 Aug 20.
7
The role of extra-corporeal membrane oxygenation (ECMO) in the treatment of diffuse alveolar haemorrhage secondary to ANCA-associated vasculitis: report of two cases and review of the literature.体外膜肺氧合（ECMO）在治疗抗中性粒细胞胞质抗体（ANCA）相关性血管炎继发弥漫性肺泡出血中的作用：两例报告并文献复习。
Rheumatol Int. 2019 Feb;39(2):367-375. doi: 10.1007/s00296-018-4116-z. Epub 2018 Aug 3.
8
Effect of plasma exchange on in-hospital mortality in patients with pulmonary hemorrhage secondary to antineutrophil cytoplasmic antibody-associated vasculitis: A propensity-matched analysis using a nationwide administrative database.血浆置换对抗中性粒细胞胞浆抗体相关性血管炎相关肺出血患者住院死亡率的影响：基于全国性行政数据库的倾向性匹配分析。
PLoS One. 2018 Apr 23;13(4):e0196009. doi: 10.1371/journal.pone.0196009. eCollection 2018.
9
Eosinophilic granulomatosis with polyangiitis (formerly known as Churg-Strauss syndrome) as a differential diagnosis of hypereosinophilic syndromes.嗜酸性肉芽肿性多血管炎（原称变应性肉芽肿性血管炎）作为高嗜酸性粒细胞综合征的鉴别诊断。
Respir Med Case Rep. 2017 Mar 8;21:1-6. doi: 10.1016/j.rmcr.2017.03.006. eCollection 2017.
10
Pneumo-Renal Syndrome in Anti- Neutrophil Cytoplasm Antibody (ANCA)-Associated Small-Vessel Vasculitis.抗中性粒细胞胞浆抗体（ANCA）相关小血管炎中的肺肾综合征
Maedica (Bucur). 2015 Jun;10(2):101-106.
本文引用的文献
1
PROLONGED SURVIVAL IN GOODPASTURE'S SYNDROME.
Arch Intern Med. 1964 Sep;114:453-60. doi: 10.1001/archinte.1964.03860090187024.
2
A standardized breath holding technique for the clinical measurement of the diffusing capacity of the lung for carbon monoxide.一种用于临床测量肺一氧化碳弥散能力的标准化屏气技术。
J Clin Invest. 1957 Jan;36(1 Part 1):1-17. doi: 10.1172/JCI103402.
3
Serial estimations of carbon monoxide diffusing capacity in intrapulmonary haemorrhage.
Clin Sci (Lond). 1981 May;60(5):507-12. doi: 10.1042/cs0600507.
4
Wegener's granulomatosis: observations on 18 patients with severe renal disease.韦格纳肉芽肿病：18例重症肾病患者的观察
Q J Med. 1983 Autumn;52(208):435-60.
5
Alveolar hemorrhage syndromes: diffuse microvascular lung hemorrhage in immune and idiopathic disorders.肺泡出血综合征：免疫性和特发性疾病中的弥漫性微血管肺出血
Medicine (Baltimore). 1984 Nov;63(6):343-61.
6
Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.韦格纳肉芽肿病：85例患者21年的前瞻性临床与治疗经验
Ann Intern Med. 1983 Jan;98(1):76-85. doi: 10.7326/0003-4819-98-1-76.
7
Cigarette smoking and lung haemorrhage in glomerulonephritis caused by autoantibodies to glomerular basement membrane.
Lancet. 1983 Dec 17;2(8364):1390-3. doi: 10.1016/s0140-6736(83)90923-6.
8
Prognosis after immunosuppression of patients with crescentic nephritis requiring dialysis.
Lancet. 1983 Feb 5;1(8319):263-5. doi: 10.1016/s0140-6736(83)91685-9.
9
Iron-deficiency anaemia: its effect on transfer factor for the lung (diffusing capacity) and ventilation and cardiac frequency during sub-maximal exercise.缺铁性贫血：其对次极量运动期间肺转移因子（弥散能力）、通气及心率的影响。
Clin Sci. 1972 Mar;42(3):325-35. doi: 10.1042/cs0420325.
10
Anti-glomerular basement membrane antibody-induced glomerulonephritis.抗肾小球基底膜抗体诱导的肾小球肾炎。
Kidney Int. 1973 Feb;3(2):74-89. doi: 10.1038/ki.1973.14.
Zotero 插件