肺出血并发韦格纳肉芽肿和显微镜下多动脉炎。
Pulmonary haemorrhage complicating Wegener's granulomatosis and microscopic polyarteritis.
作者信息
Haworth S J, Savage C O, Carr D, Hughes J M, Rees A J
出版信息
Br Med J (Clin Res Ed). 1985 Jun 15;290(6484):1775-8. doi: 10.1136/bmj.290.6484.1775.
Abstract
The incidence and characteristics of pulmonary haemorrhage in a series of 89 patients with systemic vasculitis were analysed. Pulmonary haemorrhage occurred in 32 of these patients and was associated with haemoptysis in all 32, alveolar shadowing in the chest radiograph in 28, and a significantly raised transfer coefficient in 30. Pulmonary haemorrhage usually resolved with treatment by immunosuppressive drugs but was the cause of death in 11 patients. In contrast with patients with antibasement membrane antibodies there was no correlation between pulmonary haemorrhage and cigarette smoking. Pulmonary haemorrhage is a cause of serious morbidity in patients with systemic vasculitis.
摘要
分析了89例系统性血管炎患者肺出血的发生率及特征。这些患者中有32例发生肺出血，所有32例均伴有咯血，28例胸部X线片有肺泡阴影，30例转运系数显著升高。肺出血通常经免疫抑制药物治疗后缓解，但11例患者死于肺出血。与抗基底膜抗体患者不同，肺出血与吸烟之间无相关性。肺出血是系统性血管炎患者严重发病的原因之一。
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