Reves R, Budgett R, Miller D, Wadsworth J, Haines A
Br Med J (Clin Res Ed). 1985 Jun 29;290(6486):1953-6. doi: 10.1136/bmj.290.6486.1953.
Tympanometry was used to provide evidence of middle ear effusions in a prospective study of middle ear disease in 264 children aged 3 months to 6 years in general practice. Adequate measurements on both ears were obtained in 220 children, of whom 68 (31%) had evidence of middle ear effusion in one ear (29 children) or both ears (39 children) at entry to the study. In 28 (42%) of the 68 children persistence of the tympanometric findings was recorded for at least three months. Children of European descent were more likely to have evidence of middle ear effusion at the initial examination compared with African and West Indian children, as were those children whose siblings had a positive history of otitis media compared with those whose siblings had no such history. Children under 3 years were more likely to have evidence of an effusion than older children. Middle ear effusion as shown by tympanometry was not associated with a previous history of otitis media in the child but was associated with recent symptoms of respiratory infection or otalgia. A previous consultation for otitis media was, however, strongly associated with a greater likelihood of a consultation for otitis media during the follow up period. Comparing evidence of effusion by tympanometry with that by pneumatic otoscopy showed that using the appearance of the eardrum alone the sensitivity of otoscopy was 55%; the addition of mobility improved the sensitivity to 76% with little reduction in specificity. Further studies on populations using tympanometry are needed to determine the natural history, aetiology, and indications for referring children with middle ear effusion.
在一项针对普通诊所中264名3个月至6岁儿童中耳疾病的前瞻性研究中,采用鼓室导抗图来提供中耳积液的证据。220名儿童双耳均获得了充分测量数据,其中68名(31%)儿童在研究开始时,有一只耳朵(29名儿童)或双耳(39名儿童)存在中耳积液的证据。在这68名儿童中,28名(42%)的鼓室导抗图结果持续至少三个月。与非洲和西印度儿童相比,欧洲裔儿童在初次检查时更有可能有中耳积液的证据;与兄弟姐妹无中耳炎阳性病史的儿童相比,兄弟姐妹有中耳炎阳性病史的儿童也是如此。3岁以下儿童比大龄儿童更有可能有积液证据。鼓室导抗图显示的中耳积液与儿童既往中耳炎病史无关,但与近期呼吸道感染或耳痛症状有关。然而,既往因中耳炎就诊与随访期间因中耳炎就诊的可能性大大增加密切相关。将鼓室导抗图显示的积液证据与鼓膜气耳镜检查结果相比较,结果表明,仅根据鼓膜外观,耳镜检查的敏感性为55%;增加鼓膜活动度后,敏感性提高到76%,而特异性降低不多。需要对使用鼓室导抗图的人群进行进一步研究,以确定中耳积液儿童的自然病程、病因及转诊指征。