Department of Oral and Cranio-Maxillofacial Surgery, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Glueckstrasse 11, 91054, Erlangen, Germany.
Institute of Medical Teaching and Medical Education Research, University Hospital of Würzburg, Würzburg, Germany.
Clin Oral Investig. 2024 Sep 7;28(10):516. doi: 10.1007/s00784-024-05908-8.
This study analyzed the human maxilla to support the development of mean-value-based cutting guide systems for maxillary reconstruction, bridging the gap between freehand techniques and virtual surgical planning (VSP).
This retrospective cohort study used routine CT scans. DICOM data enabled 3D modelling and the maxilla was divided into four regions: paranasal (R1), facial maxillary sinus wall (R2), zygomatic bone (R3) and alveolar process (R4). Surface comparisons were made with a reference skull. Statistical analyses assessed anatomical variations, focusing on mean distance (Dmean), area of valid distance (AVD), integrated distance (ID) and integrated absolute distance (IAD). The study addressed hemimaxillectomy defects for two-segmental reconstructions using seven defined bilateral points to determine segmental distances and angles.
Data from 50 patients showed R2 as the most homogeneous and R4 as the most heterogeneous region. Significant age and gender differences were found in R3 and R4, with younger patients and females having more outliers. Cluster analysis indicated that males had R1 and R3 positioned anterior to the reference skull. The mean angle for segmental reconstruction was 131.24° ± 1.29°, with anterior segment length of 30.71 ± 0.57 mm and posterior length of 28.15 ± 0.86 mm.
Anatomical analysis supported the development of semistandardized segmental resection approaches. Although gender and anatomical differences were noted, they did not significantly impact the feasibility of mean-value-based cutting-guide systems.
This study provides essential anatomical data for creating cost-effective and efficient reconstruction options for maxillary defects, potentially improving surgical outcomes and expanding reconstructive possibilities beyond current techniques.
本研究分析了人类上颌骨,旨在为上颌骨重建开发基于均值的切割引导系统,从而缩小徒手技术与虚拟手术规划(VSP)之间的差距。
这是一项回顾性队列研究,使用了常规 CT 扫描。DICOM 数据可实现 3D 建模,并将上颌骨分为四个区域:鼻旁(R1)、面上颌窦壁(R2)、颧骨(R3)和牙槽突(R4)。与参考颅骨进行表面比较。统计分析评估了解剖学变异,重点关注平均距离(Dmean)、有效距离面积(AVD)、积分距离(ID)和积分绝对距离(IAD)。该研究针对两段式重建的半上颌骨切除术缺陷,使用七个定义的双侧点来确定节段距离和角度。
来自 50 名患者的数据显示,R2 是最同质的区域,而 R4 是最异质的区域。在 R3 和 R4 中发现了显著的年龄和性别差异,年轻患者和女性的离群值更多。聚类分析表明,男性的 R1 和 R3 在前颅底的前面。节段重建的平均角度为 131.24°±1.29°,前节段长度为 30.71±0.57mm,后节段长度为 28.15±0.86mm。
解剖学分析支持半标准化节段切除方法的发展。尽管存在性别和解剖差异,但它们并未显著影响基于均值的切割引导系统的可行性。
本研究为上颌骨缺损提供了创建具有成本效益和高效的重建方案的重要解剖数据,有可能改善手术结果,并在现有技术之外扩展重建可能性。