School of Dentistry, Qom University of Medical Sciences, Qom, Iran.
Department of Microbiology, Parasitology and Immunology, School of Medicine, Qom University of Medical Sciences, Qom, Iran.
BMC Oral Health. 2024 Sep 8;24(1):1052. doi: 10.1186/s12903-024-04820-7.
Mineral Trioxide Aggregate (MTA) is one of the main retrograde filling materials that is used today as a root end filling material and perforation repair material. This study was conducted with the aim of investigating the antibacterial and antifungal properties of four types of bio-ceramic materials, AGM MTA, Ortho MTA, Pro root MTA and Cem cement for oral and dental health.
In this study, the antibacterial activity of four types of bio-ceramic materials against two bacterial strains of Enterococcus faecalis (ATTC 29212), Escherichia coli (ATTC 35318) and antifungal activity against Candida albicans (ATTC 10231) were investigated using the well diffusion method.
In the context of the relationship between the type of microorganism and the diameter of the growth inhibitory zone for each type of bio-ceramic material, there was no significant difference for Enterococcus faecalis, and a significant difference was observed for Escherichia coli and Candida albicans (p < 0.05).
The results show that each of the bio-ceramic materials AGM, Pro root, Cem cement and Ortho have antibacterial and antifungal properties. AGM MTA bio-ceramic material on Candida albicans fungus and Ortho MTA bio-ceramic material had the most effect on Escherichia coli bacteria. Therefore, the mentioned bio-ceramic materials can play a significant role in oral and dental health by providing a suitable material for restoration.
矿物三氧化物聚合体（MTA）是目前主要的逆行填充材料之一，可用作根管填充材料和穿孔修复材料。本研究旨在研究四种生物陶瓷材料（AGM MTA、Ortho MTA、Pro root MTA 和 Cem 水泥）的抗菌和抗真菌特性，以促进口腔和牙齿健康。
在这项研究中，使用琼脂扩散法研究了四种生物陶瓷材料对粪肠球菌（ATTC 29212）和大肠杆菌（ATTC 35318）两种细菌菌株的抗菌活性以及对白色念珠菌（ATTC 10231）的抗真菌活性。
在每种生物陶瓷材料与微生物类型和生长抑制带直径之间的关系方面，粪肠球菌没有差异，而大肠杆菌和白色念珠菌有差异（p<0.05）。
结果表明，AGM、Pro root、Cem 水泥和 Ortho 这四种生物陶瓷材料均具有抗菌和抗真菌特性。AGM MTA 生物陶瓷材料对白色念珠菌真菌和 Ortho MTA 生物陶瓷材料对大肠杆菌细菌的作用最大。因此，所述生物陶瓷材料可通过提供合适的修复材料在口腔和牙齿健康方面发挥重要作用。
