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运用基于适应性选择的联合分析方法促进骨关节炎管理中的共同决策:一项患者认知研究。

Using Adaptive Choice-Based Conjoint Approach to Facilitate Shared Decision-Making in Osteoarthritis Management: A Patient Perception Study.

作者信息

Al-Omari Basem, Farhat Joviana, Odeh Mohanad, Khan Mumtaz, Grancharov Hristo, Abu Zahr Zaki, Hanna Sammy, Alrahoomi Abdulla

机构信息

Khalifa University, Abu Dhabi, United Arab Emirates.

Department of Clinical Pharmacy and Pharmacy Practice Faculty of Pharmaceutical Sciences, The Hashemite University, Zarqa, Jordan.

出版信息

Arthritis Care Res (Hoboken). 2025 Feb;77(2):240-250. doi: 10.1002/acr.25429. Epub 2024 Oct 17.

Abstract

OBJECTIVE

This study examines the application of the adaptive choice-based conjoint (ACBC) method to facilitate the shared decision-making (SDM) process for osteoarthritis (OA) treatment.

METHODS

The study recruited adult patients with OA attending the rheumatology/orthopedics clinics in a local urban hospital in Abu Dhabi, United Arab Emirates (UAE). Participants completed a questionnaire regarding who influences their decision in selecting OA medication, followed by an ACBC questionnaire about OA medication preferences and a questionnaire about the potential contribution of ACBC to the SDM process. A univariate analysis was used to investigate the relationships between participant variables and factors that influence their decision-making processes. The chi-squared test, Fisher's exact test, Cramér's V coefficient test, and multivariable logistic regression analysis were used. The primary outcome investigates the contribution of the ACBC method to the SDM process for OA treatment. Secondary outcomes measure the association between patient demographics and variables related to the SDM process and ACBC questionnaire.

RESULTS

Five hundred patients participated in this study, with a response rate of 100%. Most study participants were 60 to 69 years old (34.8%), women (78.8%), and UAE nationals (90.4%). Patients' opinions and online or paper information influencing their decision in selecting OA medication had a statistically significant association with age, gender, education, and employment (P = 0.001, P = 0.039, P = 0.002, and P = 0.001, respectively). Employment status showed the strongest association (φc 0.170) with being independent in making the decision about OA medications, whereas education levels showed the strongest association (φc 0.24) with decisions impacted by online or paper information. The results of the multivariable logistic analysis showed that the only statistically significant variable for online or paper information that influenced the decision in selecting OA medication was education level (P = 0.003). Most participants agreed or strongly agreed that the ACBC predicted their preferences for OA treatment (96.8%) and that the questionnaire may help doctors understand patient preferences (93%), and they recommended the use of the ACBC tool in doctors' clinics to aid the SDM process (92.8%) between patients and their physicians.

CONCLUSION

An ACBC approach can facilitate doctors' understanding of patient preferences and aid the SDM process. Most patients with OA are independent or influenced by their physician when making decisions about OA medication. Higher education and employment among patients with OA are associated with a better involvement in the SDM process for available treatment.

摘要

目的

本研究探讨适应性基于选择的联合分析(ACBC)方法在促进骨关节炎(OA)治疗的共同决策(SDM)过程中的应用。

方法

该研究招募了在阿拉伯联合酋长国(UAE)阿布扎比一家当地城市医院的风湿病/骨科诊所就诊的成年OA患者。参与者完成了一份关于在选择OA药物时谁影响他们决策的问卷,随后是一份关于OA药物偏好的ACBC问卷以及一份关于ACBC对SDM过程潜在贡献的问卷。采用单变量分析来研究参与者变量与影响其决策过程的因素之间的关系。使用卡方检验、费舍尔精确检验、克莱默V系数检验和多变量逻辑回归分析。主要结果调查ACBC方法对OA治疗的SDM过程的贡献。次要结果衡量患者人口统计学与与SDM过程和ACBC问卷相关的变量之间的关联。

结果

500名患者参与了本研究,回复率为100%。大多数研究参与者年龄在60至69岁之间(34.8%),为女性(78.8%),是阿联酋国民(90.4%)。患者在选择OA药物时影响其决策的意见以及在线或纸质信息与年龄、性别、教育程度和就业情况具有统计学上的显著关联(分别为P = 0.001、P = 0.039、P = 0.002和P = 0.001)。就业状况与独立做出OA药物决策的关联最强(φc 0.170),而教育程度与受在线或纸质信息影响的决策关联最强(φc 0.24)。多变量逻辑分析结果表明,影响选择OA药物决策的在线或纸质信息的唯一具有统计学意义的变量是教育程度(P = 0.003)。大多数参与者同意或强烈同意ACBC预测了他们对OA治疗的偏好(96.8%),并且该问卷可能有助于医生了解患者偏好(93%),他们建议在医生诊所使用ACBC工具以辅助患者与其医生之间的SDM过程(92.8%)。

结论

ACBC方法可以促进医生对患者偏好的理解并辅助SDM过程。大多数OA患者在做出OA药物决策时是独立的或受其医生影响。OA患者中较高的教育程度和就业与更好地参与现有治疗的SDM过程相关。

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