Chong Chun Wie, Liew Mei Shan, Ooi Weitze, Jamil Hassan, Lim Angie, Hooi Suet Li, Tay Clarisse S C, Tan Gwendoline
School of Pharmacy, Monash University Malaysia, Subang Jaya, Malaysia.
Dole Specialty Ingredients, Dole Asia Holdings Pte., Ltd., Singapore, Singapore.
Front Nutr. 2024 Aug 23;11:1437645. doi: 10.3389/fnut.2024.1437645. eCollection 2024.
To determine whether green banana powder (GBP) and pineapple fibre powder (PFP) promote beneficial bacterial species, directly improve human gut health and modulate the gut microbiome and understand their utility as functional foods and dietary supplements.
Over 14 days, 60 adults followed protocol requirements, completed food diaries and study questionnaires, avoided consuming supplements with prebiotics, probiotics or postbiotics, and ingested food containing 5 g of total daily fibre [placebo (10.75 g), GBP (10.75 g) or PFP (7.41 g)]. Participants' medical and baseline wellness histories, as well as stool samples, were collected at baseline, day 7 and 14. Stool DNA was processed for sequencing.
Dietary fibre and resistant starches (RS) in GBP and PFP promoted temporal increases in beneficial bacteria. GBP significantly elevated 7 species (, , , , , , and ), while PFP enriched 6 species (, , , , , and ). These bacteria, found to be deficient in younger adults, were promoted by both powders. PFP benefitted both genders aged 16-23, while GBP benefitted overweight/obese individuals, including females. GBP and PFP fiber and RS improved bowel regularity and health as well as metabolism by promoting histidine, branched-chain amino acids, short-chain fatty acids, and biotin production. The additional fiber caused "low" bloatedness and reduced "fairly bad" sleep disruptions, without affecting sleep durations.
GBP and PFP supplementation increased beneficial bacteria and metabolites, improved host gut health, and present a valuable nutritional strategy for enhancing human health.
AMILI Institutional Review Board, Identifier 2023/0301.
确定绿香蕉粉（GBP）和菠萝纤维粉（PFP）是否能促进有益细菌种类的生长，直接改善人体肠道健康并调节肠道微生物群，并了解它们作为功能性食品和膳食补充膳食补充剂的效用。
在14天的时间里，60名成年人遵循方案要求，完成食物日记和研究问卷，避免食用含有益生元、益生菌或合生元的补充剂，并摄入每天总膳食纤维含量为5克的食物[安慰剂（10.75克）、GBP（10.75克）或PFP（7.41克）]。在基线、第7天和第14天收集参与者的病史和基线健康状况，以及粪便样本。对粪便DNA进行测序处理。
GBP和PFP中的膳食纤维和抗性淀粉促进了有益细菌的暂时增加。GBP显著增加了7种细菌（[具体细菌种类1]、[具体细菌种类2]、[具体细菌种类3]、[具体细菌种类4]、[具体细菌种类5]、[具体细菌种类6]和[具体细菌种类7]），而PFP富集了6种细菌（[具体细菌种类8]、[具体细菌种类9]、[具体细菌种类10]、[具体细菌种类11]、[具体细菌种类12]和[具体细菌种类13]）。这些在年轻人中发现不足的细菌，两种粉末都能促进其生长。PFP对16 - 23岁的男女都有益，而GBP对超重/肥胖个体有益，包括女性。GBP和PFP中的纤维和抗性淀粉通过促进组氨酸、支链氨基酸、短链脂肪酸和生物素的产生，改善了肠道规律性、健康状况以及新陈代谢。额外摄入的纤维导致“轻微”腹胀，并减少了“相当严重”的睡眠干扰，但不影响睡眠时间。
补充GBP和PFP可增加有益细菌和代谢产物，改善宿主肠道健康，并为增强人类健康提供了一种有价值的营养策略。
AMILI机构审查委员会标识符2023/0301。
