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无论个体状况如何,梅毒都不应被忽视。

Syphilis Should not be Overlooked in any Individual, Irrespective of their Condition.

作者信息

Cellier Oriane, Jourdan Juliette, Dahmane Lotfi, Perronne Véronique, Dinh Aurélien, Jaffal Karim

机构信息

Internal Medicine Resident, Paris-Est Créteil Université, Paris, France.

Infectious Disease Department, Raymond-Poincaré University Hospital, AP-HP, Paris Saclay University, Garches, France.

出版信息

Eur J Case Rep Intern Med. 2024 Aug 5;11(9):004578. doi: 10.12890/2024_004578. eCollection 2024.

DOI:10.12890/2024_004578
PMID:39247235
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11379106/
Abstract

INTRODUCTION

Syphilis remains a significant challenge in public health, largely because of its diverse clinical manifestations, often resulting in underdiagnosis especially among patients with neurogenic disability.

CASE DESCRIPTION

We present a case of neurosyphilis in a 63-year-old patient with a spinal cord injury. Despite syphilis being a well-established sexually transmitted infection, the exacerbation of neurological and dermatological symptoms during physical examination prompted an investigation into alternative causes beyond the patient's pre-existing paraparesis, ultimately resulting in the diagnosis of neurosyphilis.

CONCLUSION

This case highlights the importance of considering syphilis as a potential diagnosis in individuals regardless of their medical history.

LEARNING POINTS

The incidence of syphilis cases is on the rise, presenting an ongoing challenge.Faced with atypical neurological symptomatology, it is necessary to know how to investigate and discuss tertiary syphilis.In the event of neurological worsening in a neuro-injured patient, it is necessary to know how to discuss a curable diagnosis.

摘要

引言

梅毒仍然是公共卫生领域的一项重大挑战,很大程度上是因为其临床表现多样,常常导致漏诊,尤其是在神经源性残疾患者中。

病例描述

我们报告一例63岁脊髓损伤患者的神经梅毒病例。尽管梅毒是一种广为人知的性传播感染,但体格检查期间神经和皮肤症状的加重促使对患者既往截瘫之外的其他病因进行调查,最终确诊为神经梅毒。

结论

该病例凸显了无论个人病史如何,都应将梅毒视为潜在诊断的重要性。

学习要点

梅毒病例的发病率正在上升,这是一个持续存在的挑战。面对非典型神经症状,有必要知道如何调查和讨论三期梅毒。在神经损伤患者出现神经功能恶化的情况下,有必要知道如何探讨可治愈的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e869/11379106/33bc58e5ca47/4578_Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e869/11379106/96af2c652c3a/4578_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e869/11379106/33bc58e5ca47/4578_Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e869/11379106/96af2c652c3a/4578_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e869/11379106/33bc58e5ca47/4578_Fig2.jpg

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Potential impact of doxycycline post-exposure prophylaxis prescribing strategies on incidence of bacterial sexually transmitted infections.多西环素暴露后预防用药策略对细菌性性传播感染发病率的潜在影响。
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