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多组分运动与有氧运动干预:对成年及老年心血管疾病患者血流动力学、身体素质和生活质量的影响:一项随机对照研究。

Multicomponent versus aerobic exercise intervention: Effects on hemodynamic, physical fitness and quality of life in adult and elderly cardiovascular disease patients: A randomized controlled study.

作者信息

Poli Luca, Greco Gianpiero, Cataldi Stefania, Ciccone Marco Matteo, De Giosa Annamaria, Fischetti Francesco

机构信息

Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Study of Bari, 70124, Bari, Italy.

Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Study of Bari, 70124, Bari, Italy.

出版信息

Heliyon. 2024 Aug 13;10(16):e36200. doi: 10.1016/j.heliyon.2024.e36200. eCollection 2024 Aug 30.

Abstract

OBJECTIVE

Cardiovascular diseases (CVDs) remain a leading cause of mortality globally, emphasizing the need for effective preventive measures. This study aimed to investigate the effects of a multicomponent compared to an aerobic training program on the hemodynamic parameters, physical fitness, psychophysical health status and quality of life (QoL) of adults and elderly with stabilized CVDs.

METHODS

Thirty-three subjects (19M and 14F; age 69.5 ± 4.9 years; BMI 27.34 ± 4.95 kg/m2) suffering from CVDs voluntarily participated in this 10-week randomized controlled study and were allocated into three groups: multicomponent training group (MTG; 6M, 6F; cardiorespiratory, resistance, flexibility and breathing exercises; 60', 2d·wk-1), aerobic training group (ATG; 7M, 5F; aerobic-only training; 60', 2d·wk-1) or a wait-list control group (CG; 6M, 3F; no PA). Hemodynamic parameters were assessed through resting hearth rate (RHR) and peripheral-systolic and diastolic blood pressure (P-SBP/P-DBP). Physical fitness was assessed via a 30" chair stand test (30CST), timed up and go (TUG) test, handgrip strength (HGS) test, and 2' step test (TMST). The health status, QoL and enjoyment were evaluated with short form-12 (SF-12), world health organization quality of life-bref (WHOQoL-bref) and physical activity enjoyment scale (PACES), respectively.

RESULTS

After the intervention, MTG showed significant improvements in hemodynamic parameters (95 % CI, RHR: 2.76 to 9.07; P-SBP: 3.28 to 13.71; P-DBP: 3.56 to 8.94; p < 0.001), physical fitness (95 % CI, 30CST: 4.42 to -1.90; TUG: 0.56 to 1.58; TMST: 35.24 to -18.58; Dominant HGS: 4.00 to -1.65; Undominant HGS: 2.87 to -0.79, p < 0.001) and enjoyment (PACES: 15.18 to -5.48, p < 0.001) compared to CG; ATG showed significant improvement in hemodynamic parameters (95 % CI, RHR: 1.76 to 8.07; P-SBP: 3.19 to 13.63; P-DBP: 4.47 to 9.85, p < 0.001), physical fitness (95 % CI, 30CST: 2.59 to -0.07; TUG: 0.03 to 1.05; Dominant HGS: 2.42 to -0.07, p < 0.05; TMST: 36.08 to -19.41, p < 0.001) and enjoyment (PACES: 14.68 to -4.98, p < 0.001) compared to CG. No significant changes were observed in QoL and SF-12 (p > 0.05). Significant differences between MTG and ATG were only found in physical fitness variables (95 % CI, 30CST: 3.21 to -0.45, p < 0.01; Dominant HGS: 0.00 to 3.00, p < 0.05).

CONCLUSIONS

Findings showed significant improvements in hemodynamic parameters and physical fitness suggesting the effectiveness of the multicomponent exercise program, similar to aerobic-only training, and greater efficacy for lower limb strength and dominant hand grip strength in adults and elderly with stabilized CVDs. Both exercise groups showed similar levels of enjoyment.

摘要

目的

心血管疾病(CVDs)仍是全球主要的死亡原因,这凸显了采取有效预防措施的必要性。本研究旨在调查多组分训练计划与有氧运动训练计划相比,对患有稳定型心血管疾病的成年人和老年人的血流动力学参数、体能、心理生理健康状况和生活质量(QoL)的影响。

方法

33名患有心血管疾病的受试者(19名男性和14名女性;年龄69.5±4.9岁;体重指数27.34±4.95kg/m²)自愿参加了这项为期10周的随机对照研究,并被分为三组:多组分训练组(MTG;6名男性,6名女性;进行心肺、抗阻、柔韧性和呼吸练习;每次60分钟,每周2天)、有氧运动训练组(ATG;7名男性,5名女性;仅进行有氧运动训练;每次60分钟,每周2天)或等待名单对照组(CG;6名男性,3名女性;不进行身体活动)。通过静息心率(RHR)以及外周收缩压和舒张压(P-SBP/P-DBP)评估血流动力学参数。通过30秒椅子站立测试(30CST)、计时起立行走测试(TUG)、握力测试(HGS)和2分钟台阶测试(TMST)评估体能。分别使用简明健康调查问卷12项量表(SF-12)、世界卫生组织生活质量简表(WHOQoL-bref)和身体活动愉悦感量表(PACES)评估健康状况、生活质量和愉悦感。

结果

干预后,与CG相比,MTG在血流动力学参数(95%CI,RHR:2.76至9.07;P-SBP:3.28至13.71;P-DBP:3.56至8.94;p<0.001)、体能(95%CI,30CST:4.42至-1.90;TUG:0.56至1.58;TMST:35.24至-18.58;优势手HGS:4.40至-1.65;非优势手HGS:2.87至-0.79,p<0.其在血流动力学参数(95%CI,RHR:1.76至8.07;P-SBP:3.19至13.63;P-DBP:4.47至9.85,p<0.001)、体能(95%CI,30CST:2.59至-0.07;TUG:0.03至1.05;优势手HGS:2.42至-0.07,p<0.05;TMST:36.08至-19.41,p<0.001)和愉悦感(PACES:14.68至-4.98,p<0.001)方面与CG相比有显著改善。生活质量和SF-12未观察到显著变化(p>0.05)。MTG和ATG之间仅在体能变量方面存在显著差异((95%CI,30CST:3.21至-0.45,p<0.01;优势手HGS:0.00至3.00,p<0.05)。

结论

研究结果表明,多组分运动计划与仅进行有氧运动训练一样,在血流动力学参数和体能方面有显著改善,并且对患有稳定型心血管疾病的成年人和老年人的下肢力量和优势手握力有更大的功效。两个运动组的愉悦感水平相似。 001)和愉悦感(PACES:15.18至-5.48,p<0.001)方面比CG有显著改善;ATG在血流动力学参数(95%CI,RHR:1.76至8.07;P-SBP:3.19至13.63;P-DBP:4.47至9.85,p<0.001)、体能(95%CI,30CST:2.59至-0.07;TUG:0.03至1.05;优势手HGS:2.42至-

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/249c/11379608/cf6c61a840c9/gr1.jpg

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