Khaleque Md Abdul, Hossain Syed Imdadul, Ali Md Romzan, Aly Saad Aly Mohamed, Abuelmakarem Hala S, Al Mamun Muhammad Shamim, Hossain Khan Md Zaved
Dept. of Chemical Engineering, Jashore University of Science and Technology Jashore 7408 Bangladesh
Laboratory of Nano-bio and Advanced Materials Engineering (NAME), Jashore University of Science and Technology Jashore 7408 Bangladesh.
RSC Adv. 2024 Sep 6;14(39):28487-28515. doi: 10.1039/d4ra04038d. eCollection 2024 Sep 4.
The lack of reliable and efficient techniques for early monitoring to stop long-term effects on human health is an increasing problem as the pathogenesis effect of infectious bacteria is growing continuously. Therefore, developing an effective early detection technique coupled with efficient and continuous monitoring of pathogenic bacteria is increasingly becoming a global public health prime target. Electrochemical biosensors are among the strategies that can be utilized for accomplishing that goal with promising potential. In recent years, identifying target biological analytes by interacting with bioreceptors modified electrodes is among the most commonly used detection techniques in electrochemical biosensing strategies. The commonly employed bioreceptors are nucleic acid molecules (DNA or RNA), proteins, antibodies, enzymes, organisms, tissues, and biomimetic components such as molecularly imprinted polymers. Despite the advancement in electrochemical biosensing, developing a reliable and effective biosensor for detecting pathogenic bacteria is still in the infancy stage with so much room for growth. A major milestone in addressing some of the issues and improving the detection pathway is the investigation of specific bacterial detection techniques. The present study covers the fundamental concepts of electrochemical biosensors, human PB illnesses, and the latest electrochemical biosensors based on bioreceptor elements that are designed to detect specific pathogenic bacteria. This study aims to assist researchers with the most up-to-date research work in the field of bio-electrochemical pathogenic bacteria detection and monitoring.
随着传染性细菌的致病作用持续增强，缺乏用于早期监测以阻止对人类健康产生长期影响的可靠且高效的技术正成为一个日益严重的问题。因此，开发一种有效的早期检测技术并对病原菌进行高效、持续的监测，正日益成为全球公共卫生的首要目标。电化学生物传感器是可用于实现该目标且具有广阔前景的策略之一。近年来，通过与修饰电极的生物受体相互作用来识别目标生物分析物是电化学生物传感策略中最常用的检测技术之一。常用的生物受体包括核酸分子（DNA或RNA）、蛋白质、抗体、酶、生物体、组织以及诸如分子印迹聚合物等仿生成分。尽管电化学生物传感取得了进展，但开发一种用于检测病原菌的可靠且有效的生物传感器仍处于起步阶段，还有很大的发展空间。解决一些问题并改进检测途径的一个重要里程碑是对特定细菌检测技术的研究。本研究涵盖了电化学生物传感器的基本概念、人类PB疾病以及基于旨在检测特定病原菌的生物受体元件的最新电化学生物传感器。本研究旨在协助研究人员开展生物电化学病原菌检测与监测领域的最新研究工作。
