Department of Traditional Chinese Medicine, The First College of Clinical Medical Science, Yichang Central People's Hospital, Three Gorges University, Yichang City, Hubei Province, China.
Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
PLoS One. 2024 Sep 9;19(9):e0310191. doi: 10.1371/journal.pone.0310191. eCollection 2024.
Intradialytic hypotension (IDH) is common in hemodialysis patients and can lead to several complications. Risk factors for IDH include demographic characteristics, comorbidities, dialysis procedure factors, and so on. Clinical studies on predictive models for dialysis-induced hypotension have shown inconsistent results. This systematic review aims to evaluate published prediction models for IDH, analyzing their characteristics, predictors, efficacy, and the methodological quality and applicability. The protocol has been prepared using the Preferred Items for Systematic Review and Meta-analysis Protocols (PRISMA-P) guidelines. The systematic review protocol for IDH prediction in hemodialysis patients has been registered with the International Platform of Registered Systematic Review and Meta-analysis Protocols (INPLASY2023110081, DOI: 10.37766/inplasy2023.11.0081). A comprehensive search across five major databases (PubMed, Web of Science, Cochrane Library, CNKI, and Wanfang) will be conducted for studies on prediction models of IDH among hemodialysis patients. Two researchers will independently screen literature, extract data, and evaluate the bias risk and applicability of included studies using prediction modelling study tools. This systematic review will provide critical insights into the efficacy and quality of reporting of the IDH model in hemodialysis patients. This will guide clinical staff in selecting the most appropriate IDH prediction model and inform future research endeavors in IDH prediction.
透析中低血压（IDH）在血液透析患者中很常见，可导致多种并发症。IDH 的危险因素包括人口统计学特征、合并症、透析程序因素等。针对透析相关性低血压预测模型的临床研究结果不一致。本系统评价旨在评估已发表的 IDH 预测模型，分析其特征、预测因素、效能以及方法学质量和适用性。该方案按照系统评价和荟萃分析首选项目报告规范（PRISMA-P）指南制定。血液透析患者 IDH 预测的系统评价方案已在国际注册系统评价和荟萃分析方案平台（INPLASY2023110081，DOI：10.37766/inplasy2023.11.0081）上注册。将对五个主要数据库（PubMed、Web of Science、Cochrane Library、CNKI 和万方）进行全面检索，以获取血液透析患者 IDH 预测模型的研究。两名研究人员将独立筛选文献、提取数据，并使用预测模型研究工具评估纳入研究的偏倚风险和适用性。本系统评价将深入了解血液透析患者 IDH 模型的效能和报告质量。这将指导临床工作人员选择最合适的 IDH 预测模型，并为未来的 IDH 预测研究提供信息。
