Wilkins D E, Hallett M, Erba G
J Neurol Neurosurg Psychiatry. 1985 Jun;48(6):506-16. doi: 10.1136/jnnp.48.6.506.
A group of patients with myoclonus is described whose jerks are preceded by a bilaterally synchronous, frontocentrally predominant, negative cerebral potential in the EEG. This potential may be a slow wave with variable timing in relation to EMG bursts, and in this circumstance the muscle jerks are usually small amplitude and multifocal ("minipolymyoclonus"). The cerebral negativity can also be shorter in duration and time-locked to limb jerks, which are larger in amplitude and more widespread. We propose that the physiology of this distinct form of myoclonus is similar to that of primary generalised epilepsy.
本文描述了一组肌阵挛患者，其抽搐之前脑电图（EEG）出现双侧同步、以额中央区为主的负性脑电活动。该电位可能是与肌电图（EMG）爆发时间关系可变的慢波，在这种情况下，肌肉抽搐通常幅度较小且多灶性发作（“微小多肌阵挛”）。脑电负性活动持续时间也可能较短，并与肢体抽搐时间锁定，后者幅度更大且分布更广。我们认为这种独特形式的肌阵挛的生理机制与原发性全身性癫痫相似。
