Public Authority of Agriculture Affairs and Fish Resources 13075 Kuwait City, Kuwait,
Public Authority of Agriculture Affairs and Fish Resources 13075 Kuwait City, Kuwait.
J Zoo Wildl Med. 2024 Sep;55(3):827-837. doi: 10.1638/2022-0045.
Nile tilapia fish skin () has been increasingly used in human and veterinary medicine in xenografts for treatment of burn wounds. The objective of this study was to self-prepare the graft using a Brazilian patent (WO2017/035615 A1) as a guide and apply it to full-thickness wounds in zoological species ( = 4). The wounds, which were all characterized as contaminated wounds in which the entire dermal layer was missing, had all previously been surgically debrided and treated with traditional wound-healing techniques without success. This graft technique was developed in response to the poor treatment success. The graft was prepared and sutured to the affected area, leading to complete contraction and epithelialization in all cases. The patients were concurrently placed on one course of systemic antibiotics because of the severity of wound contamination. The frequency of dressing changes varied between species and no adverse effects were apparent. This method of processing Nile tilapia fish skin proves promising for use in contaminated wounds, as it is inexpensive and easy to acquire and develop, mitigates stress in wildlife patients because of a decreased frequency of dressing changes and therefore handling, and can be utilized in clinical environments.
尼罗罗非鱼鱼皮 () 已越来越多地被用于异种移植以治疗烧伤创面的人类和兽医医学中。本研究的目的是使用巴西专利 (WO2017/035615 A1) 作为指导自行制备移植物，并将其应用于全层创面的动物物种 ( = 4)。所有创面均为污染创面，整个真皮层缺失，此前均已进行手术清创，并采用传统的伤口愈合技术治疗，但均未成功。这种移植技术是为了应对治疗效果不佳而开发的。将移植物制备并缝合到受影响的区域，所有情况下均导致完全收缩和上皮化。由于创面污染严重，所有患者均同时接受一疗程的全身抗生素治疗。更换敷料的频率因物种而异，没有明显的不良反应。这种处理尼罗罗非鱼鱼皮的方法在污染创面中具有应用前景，因为它价格低廉，易于获取和开发，可以减轻野生动物患者的压力，因为减少了更换敷料的频率和因此的处理次数，并且可以在临床环境中使用。
