Department of Psychology, Texas State University, 601 University Drive, San Marcos, TX 78666, USA; Department of Psychiatry, Massachusetts General Hospital, 185 Cambridge Street, Suite 2000, Boston, MA 02114, USA.
Department of Psychology, Texas State University, 601 University Drive, San Marcos, TX 78666, USA; Department of Psychiatry, Massachusetts General Hospital, 185 Cambridge Street, Suite 2000, Boston, MA 02114, USA.
J Affect Disord. 2024 Dec 15;367:678-685. doi: 10.1016/j.jad.2024.09.022. Epub 2024 Sep 8.
Pediatric OCD is associated with functional impairment in multiple environments. However, relatively little is known about the impact of comorbid conditions, as well as OCD severity on psychosocial functioning in this population. Furthermore, most studies did not include a control sample, nor examined differences between children and adolescents. The goal of this investigation was to assess psychosocial functioning and its associations with age, symptom severity, and comorbid conditions in a large well characterized sample of pediatric OCD probands, and controls.
Participants included 117 pediatric OCD probands and 147 controls, that underwent a careful diagnostic process, and completed several questionnaires and interviews.
Results revealed significant psychosocial impairments across multiple domains/settings, some of which were affected by symptom severity as well as by conduct related comorbidities and to a lesser extent affective disorders. In addition, different aspects of psychosocial impairments were found between children and adolescents.
This study provides high resolution information regarding the types and extent of psychosocial dysfunction in youth with OCD, as well as its relationship with clinical and diagnostic correlates. It is recommended that evaluation and management of OCD in youth in research and clinical settings regularly include qualitative and semi-quantitative assessment of function across these domains.
儿科强迫症与多种环境下的功能障碍有关。然而,对于共病状况以及强迫症严重程度对该人群的心理社会功能的影响,人们知之甚少。此外,大多数研究都没有包括对照组,也没有检查儿童和青少年之间的差异。本研究的目的是在一个经过精心诊断的大样本儿科强迫症患者和对照组中,评估心理社会功能及其与年龄、症状严重程度和共病状况的关系。
参与者包括 117 名儿科强迫症患者和 147 名对照组,他们接受了仔细的诊断过程,并完成了几个问卷和访谈。
结果显示,多个领域/环境存在显著的心理社会障碍,其中一些障碍受症状严重程度以及与行为相关的共病以及在较小程度上受情感障碍的影响。此外,在儿童和青少年之间发现了心理社会障碍的不同方面。
本研究提供了关于青少年强迫症患者心理社会功能障碍的类型和程度的高分辨率信息,以及其与临床和诊断相关性的关系。建议在研究和临床环境中,对青少年强迫症的评估和管理应定期包括这些领域的定性和半定量功能评估。