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成年住院患者的多病共存和衰弱状况在过去 15 年中是否发生了变化?对英格兰 1 亿 7 百万次住院的回顾性研究。

Has multimorbidity and frailty in adult hospital admissions changed over the last 15 years? A retrospective study of 107 million admissions in England.

机构信息

School of Public Health, Imperial College London, 80-92 Wood Lane, London, W12 7TA, UK.

Imperial College London Healthcare NHS Trust, St Mary's Hospital, South Wharf Road, London, W2 1NY, UK.

出版信息

BMC Med. 2024 Sep 11;22(1):369. doi: 10.1186/s12916-024-03572-z.

Abstract

BACKGROUND

Few studies have quantified multimorbidity and frailty trends within hospital settings, with even fewer reporting how much is attributable to the ageing population and individual patient factors. Studies to date have tended to focus on people over 65, rarely capturing older people or stratifying findings by planned and unplanned activity. As the UK's national health service (NHS) backlog worsens, and debates about productivity dominate, it is essential to understand these hospital trends so health services can meet them.

METHODS

Hospital Episode Statistics inpatient admission records were extracted for adults between 2006 and 2021. Multimorbidity and frailty was measured using Elixhauser Comorbidity Index and Soong Frailty Scores. Yearly proportions of people with Elixhauser conditions (0, 1, 2, 3 +) or frailty syndromes (0, 1, 2 +) were reported, and the prevalence between 2006 and 2021 compared. Logistic regression models measured how much patient factors impacted the likelihood of having three or more Elixhauser conditions or two or more frailty syndromes. Results were stratified by age groups (18-44, 45-64 and 65 +) and admission type (emergency or elective).

RESULTS

The study included 107 million adult inpatient hospital episodes. Overall, the proportion of admissions with one or more Elixhauser conditions rose for acute and elective admissions, with the trend becoming more prominent as age increased. This was most striking among acute admissions for people aged 65 and over, who saw a 35.2% absolute increase in the proportion of admissions who had three or more Elixhauser conditions. This means there were 915,221 extra hospital episodes in the last 12 months of the study, by people who had at least three Elixhauser conditions compared with 15 years ago. The findings were similar for people who had one or more frailty syndromes. Overall, year, age and socioeconomic deprivation were found to be strongly and positively associated with having three or more Elixhauser conditions or two or more frailty syndromes, with socioeconomic deprivation showing a strong dose-response relationship.

CONCLUSIONS

Overall, the proportion of hospital admissions with multiple conditions or frailty syndromes has risen over the last 15 years. This matches smaller-scale and anecdotal reports from hospitals and can inform how hospitals are reimbursed.

摘要

背景

很少有研究对医院环境中的多种合并症和虚弱趋势进行量化,更少的研究报告其归因于人口老龄化和个体患者因素的程度。迄今为止的研究往往侧重于 65 岁以上的人群,很少捕捉到老年人或按计划和非计划活动对研究结果进行分层。随着英国国民保健制度(NHS)积压问题的恶化,以及关于生产力的争论占据主导地位,了解这些医院趋势至关重要,以便卫生服务部门能够应对这些趋势。

方法

提取了 2006 年至 2021 年期间成年人的医院病例统计住院记录。使用 Elixhauser 合并症指数和 Soong 虚弱评分来衡量多种合并症和虚弱。报告了每年患有 Elixhauser 疾病(0、1、2、3+)或虚弱综合征(0、1、2+)的人数比例,并比较了 2006 年至 2021 年的患病率。使用逻辑回归模型衡量患者因素对患有三种或三种以上 Elixhauser 疾病或两种或两种以上虚弱综合征的可能性的影响。结果按年龄组(18-44、45-64 和 65+)和入院类型(急诊或择期)进行分层。

结果

该研究纳入了 1.07 亿例成年住院患者。总体而言,急性和择期入院中患有一种或多种 Elixhauser 疾病的比例有所上升,随着年龄的增长,这一趋势变得更加明显。在 65 岁及以上的急性入院患者中最为显著,他们患有三种或三种以上 Elixhauser 疾病的入院比例绝对增加了 35.2%。这意味着与 15 年前相比,在过去 12 个月的研究中,至少有三种 Elixhauser 疾病的患者额外增加了 915221 例住院。患有一种或多种虚弱综合征的患者也有类似的发现。总体而言,年份、年龄和社会经济贫困程度与患有三种或三种以上 Elixhauser 疾病或两种或两种以上虚弱综合征呈强烈且正相关,社会经济贫困程度呈强剂量反应关系。

结论

总体而言,过去 15 年来,患有多种合并症或虚弱综合征的住院患者比例有所上升。这与医院的小规模和传闻报告相吻合,并为医院的报销方式提供了信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a93/11389502/2096c0da62c8/12916_2024_3572_Fig1_HTML.jpg

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