衰弱与中年创伤患者的不良预后相关。
Frailty is associated with poor outcomes in midlife trauma patients.
作者信息
Galet Colette, Bloeser Colleen, Engelbart Jacklyn, Eyck Patrick Ten, Torner James, Skeete Dionne
机构信息
Division of Acute Care Surgery, Department of Surgery, USA.
Carver College of Medicine, USA.
出版信息
Am J Surg. 2025 Mar;241:116157. doi: 10.1016/j.amjsurg.2024.116157. Epub 2024 Dec 20.
BACKGROUND
The impact of frailty on outcomes in midlife trauma patients (50-64 y) remains understudied. We evaluated the impact of frailty on midlife trauma patients' outcomes.
METHODS
This is a retrospective cohort study using TQIP 2021 data. Demographics, injury and hospital information, comorbidities, complications, mortality, and discharge disposition were extracted. Frailty was scored using the modified frailty index-5. Multivariate analyses were performed. P < 0.001 was considered significant.
RESULTS
In 2021, 5.1 % midlife trauma patients were frail. On multivariate analysis adjusting for demographics, insurance status, injury severity score, vitals on arrival, and mode of transportation, frailty was associated with increased risk of death (OR = 2.27 [2.01-2.57]), longer hospital and ICU stay (MR = 1.46 [1.43-1.49] and MR = 1.30 [1.24-1.36]), and discharge requiring higher level of care (OR = 2.11 [2.01-2.22]).
CONCLUSION
Our data support the need for preventative efforts regarding frailty in midlife adults.
背景
衰弱对中年创伤患者（50 - 64岁）预后的影响仍未得到充分研究。我们评估了衰弱对中年创伤患者预后的影响。
方法
这是一项使用2021年创伤质量改进计划（TQIP）数据的回顾性队列研究。提取了人口统计学、损伤和医院信息、合并症、并发症、死亡率及出院处置情况。使用改良衰弱指数-5对衰弱进行评分。进行了多变量分析。P < 0.001被认为具有统计学意义。
结果
2021年，5.1%的中年创伤患者存在衰弱。在对人口统计学、保险状况、损伤严重程度评分、入院时生命体征及交通方式进行多变量分析调整后，衰弱与死亡风险增加（比值比[OR]=2.27[2.01 - 2.57]）、住院和重症监护病房（ICU）停留时间延长（平均比值[MR]=1.46[1.43 - 1.49]和MR = 1.30[1.24 - 1.36]）以及出院后需要更高水平护理（OR = 2.11[2.01 - 2.22]）相关。
结论
我们的数据支持对中年成年人衰弱问题采取预防措施的必要性。
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