Yeh-Gorocica Aaron, Torres-Castro Marco, Carrillo-Chan Claudia, Suarez-Galaz Alejandro, Suarez-Galaz Melissa, Moguel-Chin Wilson, Panti-May Alonso, Lugo-Caballero Cesar, Puerta-Guardo Henry, Chable-Santos Juan, Manrique-Saide Pablo, Ayora-Talavera Guadalupe, Selem-Salas Celia, Frias-Casas Mario, Rivero-Juarez Antonio
Laboratorio de Zoonosis y otras Enfermedades Transmitidas por Vector, Centro de Investigaciones Regionales "Dr. Hideyo Noguchi", Universidad Autonoma de Yucatan, Merida, Mexico.
Laboratorio de Enfermedades Emergentes y Reemergentes, Centro de Investigaciones Regionales "Dr. Hideyo Noguchi", Universidad Autonoma de Yucatan, Merida, Mexico.
One Health. 2024 Aug 15;19:100876. doi: 10.1016/j.onehlt.2024.100876. eCollection 2024 Dec.
(family ) and (family ) are mosquito-borne viruses that poses a significant risk to public health worldwide. Examples of these viruses include (DENV) and (ZIKV) in the genus, and (CHIKV) in the genus. The potential contribution of bats in the mosquito-to-human transmission cycle of these viral genera in the tropics has not been studied. Here, a total of 144 bats belonging to three families () and six species were captured for one year using mist nets in sites with different landscapes (forest and grassland) in the state of Yucatan, southeastern Mexico. Blood samples and rectal and oral swabs were collected to detect and RNA genomes through RT-PCR. RNA was detected in 53 individuals (36.8%; 95% CI: 29.4%-44.9%), and RNA was detected in 59 individuals (40.1%; 95% CI: 33.2%-49.2%). The sequences obtained were consistent with ZIKV and DENV, into the , and CHIKV into the positive samples. The prevalence of both and was higher during the dry season compared with the rainy season. This high positivity rate, highlighted in both and , suggests a potential contribution of bats in the circulation of these viral genera in sylvatic environments. Seasonal variation in viral genera prevalence, with higher prevalence during dry seasons than rainy seasons, may suggest specific viral activity patterns in response to climatic conditions.
黄病毒科（Flaviviridae）和披膜病毒科（Togaviridae）的病毒是通过蚊子传播的，对全球公共卫生构成重大风险。这些病毒的例子包括黄病毒属（Flavivirus）中的登革病毒（DENV）和寨卡病毒（ZIKV），以及披膜病毒属（Alphavirus）中的基孔肯雅病毒（CHIKV）。尚未研究蝙蝠在热带地区这些病毒属从蚊子到人类的传播循环中的潜在作用。在这里，在墨西哥东南部尤卡坦州不同景观（森林和草原）的地点，使用雾网捕捉了一年，共捕获了属于三个科（叶口蝠科Phyllostomidae）和六个物种的144只蝙蝠。采集血液样本以及直肠和口腔拭子，通过逆转录聚合酶链反应（RT-PCR）检测黄病毒属和披膜病毒属的RNA基因组。在53只个体（36.8%；95%置信区间：29.4%-44.9%）中检测到黄病毒属RNA，在59只个体（40.1%；95%置信区间：33.2%-49.2%）中检测到披膜病毒属RNA。获得的序列与寨卡病毒和登革病毒一致，在阳性样本中属于黄病毒属，而基孔肯雅病毒属于披膜病毒属。与雨季相比，旱季黄病毒属和披膜病毒属的流行率都更高。黄病毒属和披膜病毒属中这种高阳性率表明蝙蝠在这些病毒属在野生环境中的传播中可能发挥了作用。病毒属流行率的季节性变化，旱季高于雨季，可能表明病毒对气候条件有特定的活动模式。
