Pacific Parkinson's Research Centre, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, 2221 Wesbrook Mall, Vancouver, BC V6T2B5, Canada.
School of Audiology and Speech Sciences, Friedman Building 443, 2177 Wesbrook Mall, Vancouver, BC V6T1Z3, Canada.
Clin Neurol Neurosurg. 2024 Nov;246:108524. doi: 10.1016/j.clineuro.2024.108524. Epub 2024 Sep 2.
Hearing impairments in Parkinson's Disease (PD) have received limited attention in the past, possibly because PD patients often report no perceived hearing disability, yet negative consequences of hearing impairment might aggravate communication difficulties and social withdrawal.
Our aim was to investigate functional hearing (speech in noise recognition) in PD and evaluate its relationship to neuropsychiatric symptoms, cognition and quality of life.
Participants with PD were recruited in a tertiary movement disorder clinic. Demographic, audiological, neuropsychiatric and quality of life data were collected. Participants underwent pure tone audiometry (PTA) and Hearing in Noise test (HINT) as a part of their audiological evaluation.
A total of 29 participants (mean age: 65.8±8.3 years, M:F= 1.6:1, mean disease duration 5.2 ± 4.0 years) completed the study. All assessments were done in the ON state. 19/29 (65.5 %) participants had normal tone audiometry for age; functional hearing loss, however, was present in 17/29 (58.6 %) according to the HINT. 65 % (11/17) of the affected participants had a disease duration of <4 years. The majority (72.4 %) with poor functional hearing did not perceive any hearing impairment. Hearing deficits did not correlate with non-motor symptoms (NMS), including cognition or other quality of life measures.
Functional hearing loss is common in PD, often presents early in the disease and the majority of PD patients are unaware of their functional hearing loss. Its potential impact on cognition, communication and quality of life requires further investigation and tailored treatment.
过去，帕金森病（PD）患者的听力障碍受到的关注有限，这可能是因为 PD 患者通常报告自己没有听力障碍，但听力损伤的负面影响可能会加剧沟通困难和社交退缩。
我们旨在研究 PD 患者的功能性听力（噪声下言语识别），并评估其与神经精神症状、认知和生活质量的关系。
我们在一家三级运动障碍诊所招募了 PD 患者。收集了人口统计学、听力、神经精神和生活质量数据。参与者接受了纯音测听（PTA）和噪声下听力测试（HINT）作为其听力评估的一部分。
共有 29 名参与者（平均年龄：65.8±8.3 岁，男女比 1.6:1，平均病程 5.2±4.0 年）完成了研究。所有评估均在 ON 状态下进行。29 名参与者中有 19 名（65.5%）的纯音听力测试结果符合年龄预期；然而，根据 HINT，有 17 名（58.6%）参与者存在功能性听力损失。受影响的参与者中有 65%（11/17）的病程<4 年。大多数（72.4%）有听力障碍的患者没有感知到任何听力损伤。听力缺损与非运动症状（NMS），包括认知或其他生活质量指标无相关性。
功能性听力损失在 PD 中很常见，通常在疾病早期出现，大多数 PD 患者没有意识到自己的功能性听力损失。它对认知、沟通和生活质量的潜在影响需要进一步研究和针对性治疗。
