China-Singapore International Joint Research Institute (CSIJRI), China Singapore Guangzhou Knowledge City, Huangpu District, Guangzhou, PR China.
School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, PR China; School of Materials Science and Engineering, Nanyang Technological University, N4.1, 50 Nanyang Avenue, Singapore 639798, Singapore.
Biomater Adv. 2025 Jan;166:214023. doi: 10.1016/j.bioadv.2024.214023. Epub 2024 Sep 1.
The fisheries and aquaculture industry are known for generating substantial waste or by-products, often underutilized, or relegated to low-value purposes. However, this overlooked segment harbors a rich repository of valuable bioactive materials of which have a broad-spectrum of high-value applications. As the blue economy gains momentum and fisheries expand, sustainable exploitation of these aquatic resources is increasingly prioritized. In this review, we present a comprehensive overview of technology-enabled methods for extracting and transforming aquatic waste into valuable biomaterials and their recent advances in regenerative medicine applications, focusing on marine collagen, chitin/chitosan, calcium phosphate and bioactive-peptides. We discuss the inherent bioactive qualities of these "waste-to-resource" aquatic biomaterials and identify opportunities for their use in regenerative medicine to advance healthcare while achieving the Sustainable Development Goals.
渔业和水产养殖业以产生大量浪费或副产品而闻名，这些浪费或副产品通常未得到充分利用，或者被降级用于低价值的用途。然而，这个被忽视的领域蕴藏着丰富的有价值的生物活性物质资源，这些物质具有广泛的高价值应用。随着蓝色经济的发展和渔业的扩张，对这些水生资源的可持续开发利用日益受到重视。在这篇综述中，我们全面介绍了利用技术从水生废物中提取和转化有价值的生物材料的方法，以及它们在再生医学应用方面的最新进展，重点介绍了海洋胶原蛋白、壳聚糖/壳聚糖、磷酸钙和生物活性肽。我们讨论了这些“废物变资源”的水生生物材料的固有生物活性品质，并确定了它们在再生医学中的应用机会，以推进医疗保健，同时实现可持续发展目标。
