Mapstone R, Clark C V
Br Med J (Clin Res Ed). 1985 Jul 13;291(6488):93-5. doi: 10.1136/bmj.291.6488.93.
Oral glucose 75 g was given to 352 patients with chronic glaucoma, acute glaucoma, or ocular hypertension and 73 patients without glaucoma. The proportion of patients with shallow anterior chambers who showed an abnormal response was significantly greater than that in patients with deep anterior chambers and in the control group (p less than 0.005). The probability of developing an abnormal response to oral glucose tests increased as the depth of the anterior chamber decreased; these two variables showed a significant negative linear correlation (r = -0.79, p less than 0.001). The high prevalence of autonomic dysfunction in patients with shallow anterior chambers and glaucoma may explain this association. Because of this, acute glaucoma should be regarded as a symptom of diabetes.
对352例慢性青光眼、急性青光眼或高眼压症患者以及73例无青光眼患者给予75克口服葡萄糖。前房浅且口服葡萄糖试验反应异常的患者比例显著高于前房深的患者及对照组(p<0.005)。口服葡萄糖试验出现异常反应的概率随前房深度降低而增加;这两个变量呈显著负线性相关(r = -0.79,p<0.001)。前房浅合并青光眼患者自主神经功能障碍的高患病率可能解释了这种关联。因此,急性青光眼应被视为糖尿病的一种症状。