Clark C V, Mapstone R
Diabet Med. 1986 May;3(3):226-9. doi: 10.1111/j.1464-5491.1986.tb00749.x.
In 375 patients aged 68.5 +/- 9.4 years (mean +/- 1 SD) with primary glaucoma subdivided by irido-corneal angle configuration into closed-angle glaucoma (123 cases), ocular hypertension (186 cases), and open-angle glaucoma (66 cases), diabetic status was determined by standard 75 g oral glucose tolerance tests. In 63 patients with impaired glucose tolerance who were retested one year later, 16% had progressed to diabetes mellitus. The results confirm a significant association between non-insulin dependent diabetes mellitus and primary glaucoma which may result from autonomic dysfunction in parasympathetic tone causing anterior chamber angle closure.
在375例年龄为68.5±9.4岁（均值±1标准差）的原发性青光眼患者中，根据虹膜角膜角形态分为闭角型青光眼（123例）、高眼压症（186例）和开角型青光眼（66例），通过标准的75克口服葡萄糖耐量试验确定糖尿病状态。在63例糖耐量受损的患者中，一年后重新检测时，16%已进展为糖尿病。结果证实非胰岛素依赖型糖尿病与原发性青光眼之间存在显著关联，这可能是由于副交感神经张力的自主神经功能障碍导致前房角关闭所致。
