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超重和肥胖对 1990 年至 2021 年美国健康结果的影响。

The impact of overweight and obesity on health outcomes in the United States from 1990 to 2021.

机构信息

Department of Internal Medicine, Allegheny Health Network, Pittsburgh, Pennsylvania, USA.

Department of Physical Rehabilitation and Rehab, Montefiore Medical Center, Bronx, New York, USA.

出版信息

Diabetes Obes Metab. 2024 Nov;26(11):5455-5465. doi: 10.1111/dom.15924. Epub 2024 Sep 11.

Abstract

AIM

Elevated body mass index (BMI) presents a significant public health challenge in the United States, contributing to considerable morbidity, mortality and economic burden. This study investigates the health burden of overweight and obesity in the United States from 1990 to 2021, leveraging the Global Burden of Disease data set to analyse trends, disparities and potential determinants of high BMI-related health outcomes.

MATERIALS AND METHODS

Our study focused on the United States, analysing trends in disability-adjusted life years (DALY) and deaths attributable to high BMI, defined as a BMI of 25 kg/m or higher for adults. Statistical analyses included estimated annual percentage change (EAPC) in age-standardized DALY rates and age-standardized death rates. Pearson correlation was performed between EAPCs and the socio-demographic index (SDI), with significance set at p < 0.05.

RESULTS

From 1990 to 2021, age-standardized DALY rates attributable to high BMI increased by 24.9%, whereas the age-standardized death rates increased by 5.2%. Age disparities showed DALYs peaking at 60-64 years for males and 65-69 years for females, with deaths peaking at 65-69 years for males and 90-94 years for females. A strong negative correlation was found between the EAPC in age-standardized DALY and death rates and the SDI.

CONCLUSIONS

Overweight and obesity significantly impact public health in the United States, especially among older adults and lower socio-demographic regions. Comprehensive public health strategies integrating behavioural, technological and environmental interventions are crucial. Future research should focus on longitudinal studies, personalized interventions and policy-driven approaches to address the multifaceted influences on high BMI.

摘要

目的

在美国,升高的体重指数(BMI)带来了重大的公共卫生挑战,导致了相当多的发病率、死亡率和经济负担。本研究利用全球疾病负担数据集,调查了 1990 年至 2021 年美国超重和肥胖的健康负担,分析了与高 BMI 相关的健康结果的趋势、差异和潜在决定因素。

材料和方法

我们的研究集中在美国,分析了因高 BMI(定义为成年人 BMI 为 25kg/m2 或更高)导致的残疾调整生命年(DALY)和死亡的趋势。统计分析包括年龄标准化 DALY 率和年龄标准化死亡率的估计年平均百分比变化(EAPC)。Pearson 相关分析用于 EAPC 与社会人口指数(SDI)之间的关系,显著性水平设置为 p<0.05。

结果

从 1990 年到 2021 年,因高 BMI 导致的年龄标准化 DALY 率增加了 24.9%,而年龄标准化死亡率增加了 5.2%。年龄差异显示,男性 DALY 的峰值出现在 60-64 岁,女性的峰值出现在 65-69 岁,而男性的死亡峰值出现在 65-69 岁,女性的死亡峰值出现在 90-94 岁。发现年龄标准化 DALY 和死亡率的 EAPC 与 SDI 之间存在强烈的负相关。

结论

超重和肥胖在美国对公共卫生有重大影响,尤其是在老年人和社会人口较低的地区。综合的公共卫生策略,包括行为、技术和环境干预,是至关重要的。未来的研究应侧重于纵向研究、个性化干预和政策驱动的方法,以解决高 BMI 的多方面影响。

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